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[...]

To achieve longevity, de Grey is developing a therapy to kill cells that have lost the ability to divide, allowing healthy cells to multiply and replenish the tissue.

“The therapies that we are working on at the moment are not going to be perfect,” he said.

“These therapies are going to be good enough to take middle age people, say people aged 60, and rejuvenate them thoroughly enough so they won’t be biologically 60 again until they are chronologically 90.

“That means we have essentially bought 30 years of time to figure out how to re-rejuvenate them when they are chronologically 90 so they won’t be biologically 60 for a third time until they are 120 or 150.

“I believe that 30 years is going to be very easily enough time to do that.”

Mr de Grey explained his technique for achieving eternal youthfulness is far more likely to be developed before the theories explored by other gerontologist that focus on preventing the metabolism from causing damage to the body.

“We will be able to keep one step ahead of the problem and keep rejuvenating the same people as long as we like,” he said
“The big breakthrough in terms of publicity will be when we can take middle aged mice in the laboratory and rejuvenate them.

“Once we can do it for mice, people are going to know that it’s only a matter of time before we can do it for human beings.
“So that’s where I want to get to and I think we have a fair chance of getting there in six to eight years from now.”


http://www.news.com.au/technology/science/researchers-believe-a-biological-revolution-enabling-humans-to-experience-everlasting-youthfulness-is-coming/story-fnpjxnqt-1227304902553

Well the topic title is true. Jesus was raised from death almost 2,000 years ago, and He is still alive today... just not on planet earth physically.

:)

That would be fantastic if it's true, especially if it has none of the drawbacks a lot of ideas to do with long life have.

TA-65. Telomerase.   :)

I can imagine the outrage this would cause; given limited resources in a finite universe, coupled with the limits of time and pretty much universal demand, and the difference between rich and poor...yeah, that's a movie idea if I ever heard one, did someone make it yet?

Longevity just for the sake of it is unappealing. Our bodies age, nothing to stop that. Have you seen a 90 or 100 year old? Would you want to live 9 times longer? Even so, people aren't always so adaptable. You see older people already "lost" with tech, mainstream culture, etc, as they're in the mindset they were in decades ago. Imagine if those people (who are, likely, most of us too) lived a thousand years but we're stuck in their ways from centuries earlier.

Besides which, the chances of one reaching 120 are nearly minuscule. Till we see more reaching that plateau and exceeding it, why should we think this generation will wildly exceed it?

Not sure if you want a Wilikon continually posting new threads for the next 1000 years though...


 8)

The only way a person can live to a thousand is if he is healthy. That's the idea that de Grey is putting forward.

Since people don't want to die - I mean, just look at all the people trying to stay alive in every way they can - why not stay alive if you can do it in a healthy and happy way?

The only thing wrong is that picture of de Grey. It is self-contradictory that he should use hair coloring to keep out "de grey."

 :D

Think of all the little Wilikons there will be running around by then.    ;D

Interesting article, but I think get old is a part of the life so why 'destroy' or cancel it?

It will be the peer pressure. Even if you want to get old and die, your friends will talk you out of it.

 :D

LOL! Meh, if they get annoying there's always the ignore list like with everything, I expect I'd be just as bad and be annoying religious people for the next several hundred years if this really works.

IMO this kind of stuff are for super rich people.

Either United Nations can adopt one child policy or keep the cost of therapy so high, that lower 99% cant afford it. Problem solved.

Obviously, how can a poor/medium person pay this kind of 'cure'? Only the person rich that don't want to get old will pay for the 'experimentation'.

Am I the only one that thinks if it gets possible to live for 1000 years...
Then we will not only over populate earth faster.. But we will ruin our plantet completely within the next 200 years max.

Like those car phones.

So you are resigned to the idea that Earth land is the last explored place to live in the universe?

Ask them to call you first before they deliver.

It would be a good experiment for those who have the money to invest in this. I don't know who has lived for 150 years and as per wikipedia, the longest living human was 122 years. Basically, 70-80 years defines a normal person's age and they could use this only once.

IMO, I don't mind aging and but looking young even when I turn 60 would be most welcome. People look like 35-40 even when they are 60 years old and are quite healthy as well. Some go for cosmic surgery while some are God gifted and mainly have a healthy diet.

If they break the code for humans to live to at least a 1 000 years then by the time you'll reach your birthday science would have advanced enough for you to reach 10 000 years. By the time you'll reach 10 000 you'll be able to live to a 1 000 000 years. By the time you'll reach 1 000 000 you'll be able to live to 10 000 000 years.

Consequences? :

Life insurance companies would most likely collapse to smaller boutiques or a simple 99 cents app.

The concept of today's healthcare will be remembered as cutting edge bloodletting.

Climate change cycles of many thousands of years will be the new 4 seasons. Al gore would push hard for a ban on life beyond 3000, or erasing anything he said or wrote in his early life, 2600 years earlier.

Owning land would not make much sense because of plate tectonics. Who knows where your little paradise island will end up when you finally retire at the age of 9 236 451, underwater or 5000 feet up in the sky.

Why own a bit of land on earth when you can travel in space for centuries and own your own private moon, planet or whole solar system, for each and every human. By that time fusion reactors will be like our disposable double A batteries of today, so the energy a million year old human would need will be trivial.




 8)

Except that here are as many as 3,000 varieties of astragalus, the plant group that contains the TA-65 (telomerase) that really works to reduce aging. And this is on top of all sorts of other age reducers that work in part.

Consider grape see extract - proanthocyanidins. This product has been reducing the effects of aging for years now by its antioxidant qualities. Back in the early '90s, you couldn't even find grape seed extract. Now you can buy it relatively inexpensively - $20 a pound or less.

We have bovine pituitary extract, which helps the brain and endocrine systems by producing natural HGH in the body.

We have pregnenolone, the master hormone, which converts on demand in the body into at least 99 other hormones.

On the not so accepted side, we have MMS (chlorine dioxide) for internal use to kill of pathogens. This product has been around for over 100 years, used as drinking water purification. But we are only finding out, now, within the last 20 years or so, how it kills all kinds of bacteria and viruses throughout the whole body if taken in much stronger doses than when used for water purification. And it is close to dirt cheap.

We have ozone and H₂O₂ intravenous and direct injection therapies (generally not generally available in the USA; go to Mexico) that kill off all kinds of cancer.

Most of our natural, ground drinking water has metallic minerals in it. Metallic minerals harm and kill plants, animals and people because our bodies cannot absorb them properly. We now have fulvic acid and other humic acids that convert metallic minerals in water into ionic minerals that are actually good for you. Amazon sells fulvic acid relatively inexpensively. Fifteen years ago the price was 10 times what it is now, and you could hardly find it.

These are only a few of the things that can slow down aging right now. When TA-65 (telomerase) becomes readily available, its price will come down as well. It is happening right now a little as people realize that astragulus is available all over the place, out in nature. As this unfolds, more and more the only way that people will be able to die is if they get hit by a Mack truck.

In addition, there is all kinds of research going on to reduce aging. The only way to make money off what works is to sell it to the masses. The only way for the masses to be able to afford it is to bring the price down.

Will the 1,000-year-old person ever happen? We won't know until a thousand years are up. But many of us who are around today, may be joyfully alive on some planet revolving around a distant star, a thousand years from now.

:)

http://lunarembassy.com/about

Serious? I will buy an hectare of moon and 2 square meters of saturn. However return on topic, get old is really a part of life as be "young" or "child". Don't you want to be a young? A strange question.

From the above listed website:
Legal is not necessarily lawful. In the U.S., Canada, and the U.K. (and India, Bangladesh and Australia, as well), people who use the old common law trump anything that is legal. They trump legal because the common law is the foundation of these nations.

Take time out to find out what is really going on in the different worlds of "legal" and "lawful." Listen and become free. Listen to Karl, Bill and others in the 4 audios at http://www.youarelaw.org/common-law-discussion-karl-lentz-billy-thornton/.

:)

Nothing will change. You'll still have the young, the adult, the old. The only thing that will change is your relation to TIME. Instead of 24 hours your pocket watch will have cycles of 24 000 years...

Some trees live for multiple thousands of years. No big deal. We will be like trees, but with a home and a hammock on Ganymede.

 8)


 

It's going to take a lot of terra-forming to make Ganymede livable enough to have a hammock on it.

 :D

Hey! I got that moon for cheap. As soon as I get my hammock radiation and micro meteorite proof I'll make all upcoming posts from my new patio. 2 to 6 hrs delay for replies though, due to bad weather...  :(

Also... If we live to 1000 years and beyond, each and every life would even be more precious... and 'concretely sacred'...


 8)

You might not even need radiation proofing, as far out as Ganymede is.    :D

Especially if we were owners of countless numbers of slaves who also lived for thousands of years.

 ;D

Docile robots are cheaper to maintain in the long run, especially with Amazon Cosmos' full space debris coverage for the first 1000 years...

What I was trying to say is: would abortion still be a viable solution for creature able to live for 10000 years, when space and energy won't be an issue anymore...

 8)

Well I for one am not in the least interested in overstaying my time on earth, I lost my sense of awe a long time ago and I'm not even old. I can't bear the thought of sticking around these parts for another 1000 years, no matter how wide I stretch my imagination in terms of new tech/theories/possibilities/whatnot  :D I can totally understand that some would find a gazillion things to do though  :)

I would do anything to get my hands on something like this, but I can imagine a crap ton of movies coming out about how a drug like this ends up yazd (Yet another zombie disaster).

urrgh I can't stand it when people say "science has gone too far"

First locomotives with wagons for passengers: "Science went too far. Our internal organs won't cope with the speed..."

Abortion isn't a viable solution right now. It is the reason that people will not live for 1,000 years, no matter how good our science is. God doesn't accept murder, not even abortion murder.

:)

When people say this, they are defining "science" in the wrong way. They should be saying "engineering" rather than "science."

:)

If everyone is able to live up to 1000 years, then the earth's population will increase by 1,500%. Right now, the population is around 7.3 billion. After a millennium, we can expect some 110 billion people living on earth (provided no other planet is made suitable for human habitation by then)!

That would be like more than 100 billion more people figuring out how to make war. We'll obliterate ourselves long before we reach 110 billion pop, or anyone reaches 1000-y-o.

:)

If im stuck at the certain age for a longer period i would prefer it to be younger the better, for most of us i doubt there will be anything to help us in our time.

Faster than light travel may not be possible.  If that's true, we will never relocate to another class M planet, and we will never interact with another intelligent species.

Since we haven't met any aliens yet, we have to assume either faster than light travel is not possible, or it is possible but intelligent life (that survives its own destruction) is rare.

Hmm... population increase can be a trigger for war. Here the population is increasing and proportionally, the availability of the resources is shrinking. According to the logic, the most over-crowded nations should be the first ones to declare war (Bangladesh, Philippines.etc).

  Class M planet is a Start Trek fictional designation.  There are in fact known, habitable planets which are relatively close to earth.  Gliese 832 c, for example, is described as a Planetary Class - warm superterran, Habitable class - mesoplanet, scoring a 0.81 on the Earth Similarity Index and it's only 16.1 ly away.  No need to reach (referring to my Star Trek Warp speed chart) Warp 1 for that.  We could make it there on an impulse cruise within a human lifespan!  Who's in?
 

We always forget science and new ideas are not locked in separate vacuums. For example: the invention of concrete, then the invention of the elevator, then the invention of reinforced concrete, then the invention of sky scrappers... All together took 2000 years...

Now what is 2000 years if we can live to a 1000 years? I don't believe no other scientific discoveries will be made in a 1000 years. Propulsion, cheap energy, new "impossible" materials, etc...

Don't forget: Even if you start the treatment of living up to 1000 years at let say 70, you would gain 30 years of youth for the first time. Then the progress and the numbers of years you'll ad up will be exponential. Just like Moore's law and so many other advances in human technology (besides the pyramids and other multiple ton monuments we have yet to know how to re build but that's for another thread...)


So a "lifetime" to reach another planet or for people to get on other places, low cost space building cities, etc, will take place at the same time people will try to push back death.

I agree. If things keep on going relatively like they are now, we all can have an indefinite length of life in our future.

Longer life means more time to think without having to learn all the things over that we had already learned. A new person has to learn it all first, before he can use it to think new things.

The question has to do with all the unforeseen things that might change the present status quo. One of these is that there might be a religion that is right, and a vengeful God might crush us for not believing in Him.

:)

One of the unforeseen thing that might happen is movie stars with 156 mile long imdb.com web pages...

Only 16 light years!   ;)

The human body can only accelerate so fast.  How would you like to spend 40 years (20 speeding up, 20 slowing down) pressed into your seat at maximum acceleration?  Remember we can't get anywhere near the speed of light - the more energy we apply the more gets converted to mass.

 Yes but the acceleration need not be so great!  A constant acceleration of 5m/s² applied to the ship will create a comfortable, artificial gravity for the occupants (actually half the gravity of earth) and will attain near light speed in one year.  The ship will have traveled about 0.5 light years in that time.  If we maintain that force over the duration of the journey and point the ship in the opposite direction at the halfway point maintaining that same constant acceleration in the opposite direction, the occupants of the ship can enjoy the benefits of the artificial gravity throughout the entire journey.  Since we can't exceed the speed of light using this crude method of propulsion and current technology, the entire journey should take about 17 years.

 Also, let's say we convert the mass of the ship to energy as we go.   I'm thinking about a fusion type reactor though I don't have a mechanism for this yet but if the mass of the ship is going to increase with speed at near light speeds, we would have more fuel as well.  By the time we arrive at our destination, most of our ship would be used up and we wouldn't have to worry about recycling it.

NB I have no training in nuclear physics.

The whole ship would be like a traveling wave reactor, burning itself out while reaching its destination...

http://en.wikipedia.org/wiki/Traveling_wave_reactor

Never work. We would run into all that dark matter, and at those speeds annihilate ourselves.

 ;D

I never said I would be on that particular ship... It's not like I will be an hurry jumping in if I can live 2000 years and wait for a better technology, in my geostationary space villa...

 Dark matter is the least of our worries since we already have dark matter/energy maps to use for our travels.  We just need to chart the best path through the fields.

 http://io9.com/scientists-map-the-dark-matter-around-millions-of-galax-1698685506 (http://io9.com/scientists-map-the-dark-matter-around-millions-of-galax-1698685506)

Given that we're only going 16 ly, the maps of that region are probably very detailed already.  Now that we also have a potentially awesome propulsion system, I suggest we start a funding round.  What do you think; Bitcoin or Dogecoin?  Keep in mind we might not need this for 1000 years or more while we work out the details.  Which one is going to last?

We need a new coin that will be fulled mined 10 millions years from now... How shall we call it? Every single name I tried to come up with was already taken... :o

Well then it has to be the Wilikoin ;)

 ;D :D ;D

I shall be honored if that ever happen even if I do not deserve it...

Although it would be a fun challenge to create such a coin I guess, even if we end up living for a new average of 200 years, not 2000...

Revelation 9:6:
 ::)

I don't like the idea of Rockefeller, Soros, Buffett or any of the other criminal jerks being able to live longer than God/fate allows.

And yet you know they already are first in line $$$$...

But only first. The rest of us get the better, refined products that come later.

:)

Indeed

https://i.imgur.com/QCP3lhU.jpg

 :D

There is an  animal which can live for ever and never die, it is the immortal jellyfish, they are biologically immortal, i don't think current science can do anything to crack the code of life and death, it is though an intresting subject which facinates by going more deeper, nice attempt by that person :)

There are few more handful of animal like this upon which multiple research and studies have been carried out.

Immortal jellyfish: http://en.wikipedia.org/wiki/Turritopsis_dohrnii

http://2.bp.blogspot.com/-_aGOgV5JgFQ/UTc1TqnuqRI/AAAAAAAABgE/_IySfqjG_5Q/s1600/The+Immortal+Jellyfish.png

We can already do full hand transplants.

There seems to be (as of yet) no theoretical limitations for a full body transplant.  Give it a decade or two.

Probably the reason that Jade Helm and other police state operations exist is, it is the way that the super elite are trying to keep society from collapsing, so that investigations into longevity don't collapse along with it.

If scientific investigations are allowed to continue, and if the engineering of advanced scientific studies is allowed to expand, we will probably see methods for indefinite, healthy (no appearance of age) life coming into being. It seems that we are on the edge of finding this, both scientifically, and in our abilities to engineer it.

Reduced aging that allows long life, might exist in nature right now. If we can only dig it out and apply it...

:)

This Wikipedia article almost could have been written by Robert Klein, or by someone who follows what he says - http://frontiers-of-anthropology.blogspot.com/.

:)

EDIT: Klein blog http://globalwarming-arclein.blogspot.ca/.

That EmDrive that everyone got excited about a few months ago may actually be a warp drive! (http://www.reddit.com/r/Futurology/comments/33dqdc/that_emdrive_that_everyone_got_excited_about_a/)

That is awesome how you have experienced everything.

What parts of the world did you enjoy visiting the most? How many Asian countries did you get to visit?

ObscureBean said: "I lost my sense of awe a long time ago and I'm not even old. I can't bear the thought of sticking around these parts for another 1000 years"

I believe your answer is withing the chosen nickname ObscureBean


 8)

Is "Wilikon" the name brand of some kind of silicon carbide waterproof paper?

:)

It might very well be.

My nickname was created using multiple random online name generators... It does not mean or represent anything but this charming and oh so lovely character among us here.

 :)

You can also check out cryo preservation, where they store the body in very cold conditions for 100's of years and they revive the body after so many years, recently a little girl was preserved in cryo preservation by a company called Alcor.

Even one of the pioneers of bitcoins Hal Finney https://bitcointalk.org/index.php?action=profile;u=2436 is preserved in cryo to be revived after 50 to 100 years

http://img2.wikia.nocookie.net/__cb20140330123226/memoryalpha/en/images/8/80/Khan_in_cryotube.jpg

Revelation 20:11-15:
:)

Crude socioeconomic-hierarchy distinctions will be long forgotten by the time medical science truly defeats death.

We have the technology to get fairly close to light speed (at least greater than 1/2 light speed) if scaled up.  Unfortunately, we don't currently have the resources to do it, despite the ability.

Time with Justin Timberlake.

Really though check it out.. it is probably where we are going...

http://www.imdb.com/title/tt1637688/

Unfortunately that cant work. I didnt find the article i wanted to find because it claimed around 10 points or so why it wont be ever possible to get those persons back but i only found this video: http://bigthink.com/videos/why-cryogenics-is-bogus

We have someone spreading Christian talk after some fine Kool-Aid. Pressing the ignore button will save this thread from disaster.

Back to the topic, this is actually awesome. I'm going to guess there are a lot of people who are going to be against it. This can cause problems like overpopulation.
Let's say that this thing becomes publicly available right now, how many people would there be on the Earth in 900 years (if there are no major catastrophes or anything)?
There would have to be some kind of restrictions or something unless people want serial killers to get out of prison after 5 life sentences (if they're still 100 years?).

That can't be true because they can't know that. Ask someone from the 15th century if we're ever going to be able to fly to the moon.   ::)

Sorry I forgot all about this thread. Lol I can't tell if you're making fun or if you're serious  :D Anyways no, I haven't experienced everything. I spent some time seeking thrills, in whatever form, like everybody else, new games, gadgets, some traveling and whatnot but it soon became obvious that I could never find closure with that lifestyle. That I could spend my whole life going from thrill to thrill and at the end I would've still not even scratched the surface of possible experiences. I'd have to be immortal and even then. It's a little like the dangling carrot in front of the donkey, you try all your life but never actually get there. The thing is awe can be distilled to its essence which is exactly the same in all awe-inspiring events. You only really have to experience it once and after that you've already learned all you can possibly learn from these events. Granted it might take different people a different number of experiences to get to that point and that's perfectly fine. This usually happens with age anyways.
To answer your question, trekking in the Himalayas and I've been to a few Asian countries not that many ;)

I see what you mean but the thing is that infos are lost. What is it worth if your brain is changed or damaged so far that you are like a child or something. And that only if they can heal the damage. Cells are broken and neurons damaged. And lost infos in there cant possibly be recreated since the info is nowhere stored.

So as long as they dont find a way to store the personality or develop time travel... it wont work i think.

Adrenaline pumping thrills and gadget collecting with superficial people around you may create a void in some people's heart. Not saying it is your case though.


Others have experimented travelling millions of miles standing still...

https://i.imgur.com/Pnw47eO.jpg

We need to define what consciousness is first. Then find a way to copy it. Then find a way to transfer it. Then keeping someone's body in ice would be futile.

The most important part of "consciousness" is memory, without memory then you'd have no idea who you are, past experiences, and the like. Cryogenics at this point isn't that promising because of the degradation that occurs to the cells, but there are many other fields which are very likely(and already have had) to have huge advances in human longevity; organ transplants, bionanotechnology, bio-mechanical parts, stem cells etc.

And this is what I meant by defining what consciousness is first, as it is not just a collection of memories... If we know what it is then even trying to live up to 1000 years inside a body would become futile. We would live as long as the universe will, as pure energy (consciousness).

We have no definition of consciousness, so whatever is said may be labeled invalid. We don't even know much about memories else we would be able to modify/erase and whatnot. If we copy consciousnesses wouldn't that make it a clone and not the original? How about we define it and learn how to transfer and/or store it?

Sebastian that depends on the damage. If it is only partial we might have technology that would assume how it looked before and repair it. Don't underestimate technology.
It's actually sure if you were born in the 90s and you live till 50-60s you're going to live much more than 100 years. Advancements in nanotechnology will get rid of almost all the common causes for death like cancer, hearth diseases and such. We just have to find a way to stay younger.

http://en.wikipedia.org/wiki/Longevity_escape_velocity

Kurzweil has written a few articles about this subject as well which are worth the read for anyone who is interested.


People who say that cryonics is crap are missing the point. You see, 99% of transhumanists don't want to be cryonically preserved. They would much rather prefer to continue living. But unfortunately, sometimes an accident can happen or a person's health can deteriorate to the point where it cannot sustain itself with current medicine. Compared to cremation or burial, cryonics is the least worst option since it affords the greatest possibility of recovery. We don't know what the exact likelihood of recovery is but many signs point towards it being >0%. This is the logic behind cryonics.

Morphologically modern humans have been around for 100,000 years. Antibiotics have only been around for 80 years and modern computers for 70 years. The discovery of the double helix was only made 60 years ago and only in the last 15 or so years did we sequence our own genome. Craig's Venter's artificial cell is only 5 years old. Last year, Intel announced their 14 nm chips.

As long as science and technology continues to advance, the age of nanotechnology will arrive. How am I so sure of this? Because the proof of work already exists in the form of cellular life today. We are working, living examples of nanotechnology. The nanomachines composed of protein which fulfill vital cellular processes are a working example of nanotechnology in action:

http://s22.postimg.org/7un9r5hox/walking.jpg


No modern cryonics provider "freezes" their patients. The correct term is vitrification and unlike freezing, it preserves the neural structures intact:

http://s11.postimg.org/ai7rfi3lv/vit.jpg


Link: http://www.alcor.org/cryomyths.html

I had no idea what I was saying was already called Longevity escape velocity. Thanks for the link.

 8)

Lots (if not all) of the things in the partially quoted post are truth. But there are hidden things as well. Inside the above quote are some hidden things.

Youtube search on the name "Graham Hancock." Watch several of his videos. Look for corroborating evidence for the info in the videos. What are we looking for and finding? The worldwide evidence in archaeology, that in the past of the earth, there was a worldwide trade organization that may have been more scientifically advanced that we are... at least in some ways. It is the thing that many of us call Atlantis.

The above quote first says 100,000 years. Then it says 80 years, then 70, then 60, 15, and 5. It doesn't mention anything about the possible and potential many past times that mankind has reached a form of scientific or other greatness that has or might have surpassed our greatness of today.

Graham Hancock and others are showing the rise and fall of a worldwide civilization of mankind that suggestively happened prior to 12,500 in the past. Even if the timing and timelines are wrong, the evidence for the civilization is there.

The point? What makes us think that this time we are going to do what we failed to do in the past? True, we are going to try. But there are so many things right now in this world that indicate that if some great, worldwide catastrophe doesn't wipe us out (like what happened to Atlantis), we are on the verge of wiping ourselves out, with nukes, if nothing else. This time, we just might completely destroy all humankind from off the entire face of the earth.

Until we can do 200 years, 1,000 years along with cryogenics, is a Will-o'-the-Wisps future security. Of course, we will try. Have fun trying, or it isn't worth it.

:)

I've known plenty of oldies who were fully ready to go when the time came and there was no talk of wanting more life. I guess that's directly related to the state of their bodies in most cases.

I don't think I could tolerate thousands of years of life. The idea of it coming to a halt reasonably soon is a comforting thought sometimes.

A better solution all round would be to have your consciousness uploaded somewhere once the body has given out. No natural resources to consume and you can still experience, learn and offer some wisdom. You can also turn yourself off when things get boring and wait it out.

Thats some interesting read there, has anyone ever tried to invent something like it? Wonder how the world will be in 1000 years, if it is still there :)

As far as I know this show is the one who went the furthest into developing that idea (mixing it with a lot of actions of course).



Not for children.

Scientists have identified a drug that rejuvenates ageing muscle and brain tissue



Scientists have identified a drug that simultaneously makes ageing muscle and brain tissue in mice act young again. The research is in its very early stages, but this could represent the first step towards a treatment that restores youth to multiple parts of the body at once.

As we get older, part of the reason our bodies start failing is because adult stem cells stop replacing our damaged cells. But scientists have found that a drug known as Alk5 kinase inhibitor can perk up old stem cells in various tissue types around the body, restoring their ability to keep it young.

“We established that you can use a single small molecule to rescue essential function in not only aged brain tissue but aged muscle,” one of the research team, David Schaffer from the University of California, Berkeley Stem Cell Centre in the US, said in a press release. “That is good news, because if every tissue had a different molecular mechanism for ageing, we wouldn’t be able to have a single intervention that rescues the function of multiple tissues.”

This research is particularly exciting because, instead of focussing on individual organs, this new drug could help make the whole body, including the brain, function as if it were younger. After all, what's the point of trying to keep our bodies alive forever if our brains turn to mush after we hit 100 (and vice versa)?

The key to this process is altering the stem cell environment, which naturally changes as we get older and stops stem cells from doing their job.

A team led by Irina Conboy, also at the University of California, Berkeley, first did this in 2005, when they showed that they could infuse old mice with blood from their younger counterparts, and rejuvenate ageing stem cells. Based on this research, a study began last year to see if this approach could help treat human Alzheimer's patients.

Unfortunately, drug transfusions are impractical and can be dangerous, so the Conboy's team instead tried to find out what it was specifically in the blood of the old mice that was ageing their stem cells.

Over the past decade, one clear culprit has emerged - a growth factor known as TGF-beta1, which the team found is upregulated as we age, and suppresses stem cell activity. Publishing in the journal Oncotarget, they describe how they've finally figured out how to block its activity.

The drug Alk5 kinase inhibitor, which is already being trialled as an anticancer agent, is able to block the growth factor's receptors in mice, stopping it from ageing the body's stem cells. "This is really the first demonstration that we can find a drug that makes the key TGF-beta1 pathway, which is elevated by ageing, behave younger, thereby rejuvenating multiple organ systems," Conboy said in the release.

However, the researchers are careful to caution that this is just one biochemical pathway involved in ageing, and other cellular processes such as inflammation also play a big role in the process. They're now looking for other ways to change the stem cell environment to keep them younger for longer.

"The challenge ahead is to carefully retune the various signalling pathways in the stem cell environment, using a small number of chemicals, so that we end up recalibrating the environment to be youth-like," Conboy explained.

Once they can work out how to keep the stem cells happy, it will effectively unlock our body's own ability to heal itself and stay young indefinitely.

Of course we're a long way off that, but it's pretty exciting to think that we're finally beginning to understand how our body ages... and how to reverse the process. Because if we want to live life like Roger Sterling from Mad Men and stay perpetually young at heart, we're going to need some help.


http://www.sciencealert.com/a-drug-has-been-found-that-rejuvenates-ageing-brain-and-muscle-tissue

I wish I could take this Jesus person / myth and shove him up a Trex's ass. I truly do.
Regardless, how many of you have heard of the South african Penis transplant story ?

I don't understand you.

It is Jesus Who gave you life, when, in His pre-incarnate form He created this whole universe along with the Father.

It is He Who held the universe together when humankind sinned, and accidentally set its destruction in place.

It is He Who died on the cross and arose again to do the above.

It is He who is working on creating a better universe for us all, because this one will ultimately destroy itself; you can see it happening in the fact that all life dies.

It is He Who wants to share life, love and the new universe with you... where there will be peace and joy forever.

And you want to destroy Him?

Some of you people are really weird, and really have a death wish for yourselves.

:)

Your opinion is as valid as the Ancient Greeks that believed in their Pantheon of Gods and Goddesses. No one cares, the proof of the bible's invalidity(It's inconsistencies and contradictions) are enormous and it truly is a storybook, nothing more.

With that being said, yes the first person to live an incredibly extended lifespan could indeed already be alive right ow.

Lots of things could happen. Your opinion on the validity of the Bible is as invalid as any other opinion might be.

:)

Except it's not an opinion. The bible states incorrect things that have already been refuted, such as the age of the Earth. There are trees living right now, older than how old the bible says Earth is.

The Bible doesn't state incorrect things. It simply states things for a different purpose than unbelievers generally understand. However, on the long side, the earth is no more than 25,000 years old. Modern science that suggests that it is, is only guessing. The Bible leaves this open to an absolute max of about 25,000 years. My personal interpretations suggest a much shorter time.

:)

And there are organisms older than 25,000 years on this planet that are still alive today.

Your lack of knowledge is astounding. You take a book that's been refuted over things that have been tested thoroughly through the scientific method. You've never seen or heard god, yet you believe. Sir, that's called believing purely by faith. To believe in something by faith alone or even partly is only what fools do. You have the ability to reason, so use it.

The Devil put that science stuff here to fool us, I tell ya!

If there are living organisms that seem as old as or older than 25,000 years, nobody has been around long enough to verify the truth. Suggestions, even when backed by modern science, can't take into account nearly all the potential happenings over a 25,000 year period that might be giving science a false reading.

:)

Go study geography, archaeology, and paleontology. In fact go and become a professional in one of those fields. Once you do, then you may continue to post on this thread. Otherwise you look like one hell of an uneducated fool.

The one thing that all these disciplines have as their bottom line is that they are all "ifs." What I mean is, if things had happened in the past to have gone exactly like the studies said they did, then they might very well be correct. However, nobody knows for a fact that all these things in ancient history happened exactly the way the studies say they did. There are potential and possible changes in history, even in physics that might have affected things differently. We just don't know for sure.

:)

BADecker, you are the dumbest person I've met in my life, and that's saying something. I really hope you're trolling and don't actually believe the crap that you type...I really do.

There you go again, with the character assassination theme. You don't have a real answer, so you go and use character assassination.

:)

As I said before. You prefer to believe in a book without any evidence put into it to back up it's statements, rather than things that have been peer reviewed and tested by researches all over the world. In fact, go become a archaeologist and you can do these things yourself, such as finding out the age of rocks and plants, etc.


The whole point is that you believe in something purely from faith, which requires no evidence and are things only fools do. You do not use reason. It's like you're walking around life with your eyes closed, even though you have the chance to open them up. If you believe in god, believe in said god from logic and reason.

If you are talking about the Bible, the reports in the Bible are eye witness reports. The strong tradition of the whole nation of Israel says that the reports are true. And if you knew anything about the fastidiousness of Israel, you would see that their traditions are nothing to sneeze at. In addition, there is much science and prophesy in the Bible that has been proven true. You need to look into it a bit before you make goofy claims.

:)

Have you ever heard of that game where the teacher says something to one person the class, and by the time whatever was said reaches everyone in the class, it's something totally different from what the teacher originally said? That's what the bible is.

Show me some science the bible has in it. So called Prophecy can be found in any book, even Dr Seus, it's a technique where a computer collects words on a page and creates "prophetic statements" out of the text. Don't get fooled kiddo.

Except that Isaiah in the Dead Sea Scrolls is very similar to the current Isaiah. So things haven't changed in the Bible.

:)

I could also say my nextdoor neighbor named Moses, is very similar to Moses from the bible... Your statement means absolutely nothing.

We all know why parts of the Bible are locked in the Vatican. The best parts were picked and published. Enough now, that is off topic.
Celestio, please put him on ignore and let's get back on track.


The problem is that some things just stay in the 'research phase'. We've seen lots of examples, and lots of news appearing online. Ranging from battery technology and "elixirs of youth" that never showed up.
Stem cell research is the right way to go. The question is, are we shifting enough funds towards it? When will we see something that is ready for use?

Wow! You have a neighbor who is like 3,500 years old? Do you think he is telling the truth? Usually the women want to go the other direction... younger rather than older.

:)

I'm 26,000 years old.  A few posts up, you mentioned that nobody was around 25,000 years ago to verify things.

Well, I'm telling you I'm 26,000 years old.  What now?  Surely you wouldn't rely on evidence to suggest I might actually be in my 20's or 30's, would you?

Rather, it is shrewd politicians who are extrapolating the truth of science into all kinds of things that may or may not have happened. Then they publish their extrapolations as though they were truth, when they really don't know if their extrapolations are truth or not.

As a form of pure science, we know by experiment, right under our noses, that if you pass electricity through a brine, you get a separation of water into hydrogen and oxygen. If that is all that we know about this scientific operation, we can make all kinds of guesses as to why it works like this. Until the guesses are proven, they remain only guesses.

The brine electrolysis example is something under our noses. The things that Isaac Newton wrote about are examples we can trust even though we were not there, because we can duplicate them, because Newton was found to be a trustworthy person, and because others of his day corroborated them after they heard and saw from Newton. The things that we don't know from Newton's day are the things that were never reported by Newton or anybody else. When we see some of these things that happened back then, we can make educated guesses about them, but beyond the actual things we see, we are only guessing, even though the guesses are educated guesses.

The point is, until we KNOW about the actual truth of scientific extrapolations, until we know about the things of the distant past by going there and seeing, or by eye witness reports from other people who were there and saw, the only thing we can know is what is right under our noses.

For example, Big Bang may have happened. But it is just a story because nobody knows that there wasn't something else that happened, something else that makes us think that there was a big bang, but something else that was NOT a big bang, yet produced end results that look just the same as results that would have been produced by a big bang if it were a big bang that had caused them.

We simply do not know for sure. So, let's stop parading things as science that are only guesses.

:)

Well, if you are saying this like it is a reality, then I would have to respond that you are a liar, the part about you being 26,000 years old, that is.

:)

I can only imaging what a horrible place the world would be if all of you were around forever.  :D

The eventual demise of each and every one of us is the only thing that gives me hope for the future.  ;D

There are still places in the world that one can go to be a hermit. The advantage is, these days, that we have a few modern conveniences that a hermit can take with him to the top of his mountain that will make life easier for him.

:)

I can only imaging what a horrible place the world would be if all of us were around forever.  :D


Solidarity. Always...

 :)

Please go and educate yourself the difference between a "scientfic theory" and "guessing". If only to stop yourself from further embarassment. Thanks.  ::)

So, then, how would you devise a method to determine that I am in fact a liar and biblical claims of a 6,000 year old Earth are not lies?

You call me a liar, I call them a liar...same thing.  What now?

Imagine how bad the overpopulation problem will be when people can live that long?   Seriously, the earth only contains enough resources for so many people.   By trying to keep people alive we will be doing the opposite. 

With these breakthrews and many more coming just around the corner, firstly they will only be for the super rich to begin with but if we have rapid space developments, hopefully this helps push mankind into the galaxy and ensure we survive as a species because if we don't it doesn't matter how long we could potentially live if we are all dead threw self destruction.

They would like you to believe there is only enough resources for so many people when the truth is as always very different, the tech that is coming and has already come secretly would enable us to all live happily if we never destroy ourselves. As it stands though we are all slaves to the 'enough resources'.

PS count me out of this living passed where I am destined to live am happy growing old and dying like many before me, this is life.

In court trials, witnesses call each other liars at times. People call each other liars all over the place.

What now? Do the thing that you are best at doing... the logic of the scientific method. The scientific method really only produces the answers that we see right now. Ideas and theories are just that. Ideas and theories.

Forget prophesying the actual age of the universe. Focus on the things that are practical... so that we can actually find the ways to become healthy enough to live in pleasantness and health for 1,000 years.

:)