Easy...
1.Mastercoin - This coin has over 30Million in development money backing it. Omni wallet is going to be released soon that will put EVERY SINGLE existing wallet to shame bar NXT. Also the distributed exchange is launching around march along with Mastercoin being added to another more used exchange.
2.Bitcoin - I don't even have to state why.
3.NXT - They have just released there new decentralised exchange that truly is an innovation within the alt community. They also have large dev teams.
4. Doge
5. Protoshares - Huge company backing. Likely to be taken on by business's.
6. Karma... Because I have a S**T load of them
Regards