Are there any programs that are open-sources, could be built from sources to Linux and support GPUs, preferable also AMD GPUs support?
I checked the https://bitcointalk.org/index.php?topic=5422375.0 , but seems that all programs for GPUs are for Windows only .

the power consumption is not correct in hashrate . io and the report from hiveos. It's almost double per card, because of power needed for each CPU.

The BC-250 are looking uprofitable at the moment, with this power consumption(the watts at the wall are much higher than the software report). Anyone found another profitable usecase or how to lower the power consumption, during mining?

Which one will be most performant software to attack the #130 challenge public key?
The CPU version of keyhunt is giving me around ~35 Pkeys/sec.
 Is there a more optimal solution for GPUs?

I would say that it's less risky to keep the profits in Bitcoin and probably more risky and more profitable to keep it in Kaspa.
Kaspa have more potential for % profits. Still a lot of fundamentals are upcoming: listing on T1 exchanges, 10 blocks per seconds, KRC-20 tokens.
I would expect 2-3x gain on bitcoin and 5-10x gain on Kaspa in this bull cycle.

I also prefer MATIC/Polygon for NFTs. All the smartcontracts and Dapps from ETH could be adjust to work on Polygon. The price to upload/mint NFT on polygon is 0.00001$ compared to $2-3 on Solana.