Aside from the obvious issues of greater awareness and understanding, I think that simpler FIAT gateways will go a long way to helping with this, as a lot of people find the current options too confusing/intimidating or complicated (e.g. - to minimise fees currently I bank transfer to Revolut, exchange to Eur, send to Coinbase, send to GDAX, buy ETH & send to wallet/other exchange to buy a different altcoin).
As I've said in my previous (few) posts, I'm excited for what Ethos will bring, with the FIAT gateway rolling out in Q2, for example, but I know there's other ICOs out there looking to address this in other ways, such as Localcoinswap, which seems to be an extension of localbitcoin.

As a currency, the more retailers that can accept crypto, the greater awareness there will be, but the volatility at present makes adoption difficult. Projects like Open Platform are looking to tackle this.

I bought into Remme, but fairly small. Looks like it will need to be a long-term hold.

I'm using MEW currently, with Metamask, and it works well enough. I'm looking forward to the launch of the Ethos UW in the next few weeks though.

Hi all

Health Nexus looks like it could be good in the medium term at least; developing their own blockchain for healthcare, not just Dapps, & awareness is growing.
Loki is another one, with a really low hard-cap, but private sale only.
Open Platform should be soon too.