Having multiple different manufacturer/model video cards in my mining rigs and trying to change the core/mem clock settings using AMDOverdriveCtrl I've come upon perhaps unintended behaviour. If you try to make different profiles to use with "AMDOverdriveCtrl -i X profilename.ovdr" you may inadvertently pull profiles of the card you first ran AMDOverdriveCtrl.
This caused me some headaches with trying to automatically set the memory clock to 300 at startup on my newest card. So, I tried starting from a clean slate on all the cards in the rig, but noticed some non-matching voltage settings on the info and overdrive tabs.
Ultimately I went on a renaming/deleting spree and solved the issues. Start by making sure AMDOverdriveCtrl doesn't run at startup, comment out the lines of your various startup scripts, then restart the rig. The following command lines are run from ~/.AMDOverdriveCtrl
1. Backup the following if you'd like, by doing this:
mv Current_Startup.ovdr Current_Startup.ovdr.old
mv default.ovdr default.ovdr.old
mv VeryFirstStart.ovdr VeryFirstStart.ovdr.old
2. Run AMDOverdriveCtrl for the card you want to create a profile for and save the profile:
AMDOverdriveCtrl [-i {3,6,9,etc.}]
3. Remove the Current_Startup.ovdr and VeryFirstStart.ovdr created in the process:
rm Current_Startup.ovdr
rm VeryFirstStart.ovdr
Repeat steps 2 and 3 for each card you'd like a specific profile for and you have accurate base settings to work with for all your profiles.