How can one stop his or her Bitcoin from going up in smoke?

Bitcoin BTC was born out of a distrust for traditional markets and a desire to establish a new system, free from brokers or bankers. But as the value of many cryptocurrencies rise, so does people's uneasiness with being the only one with access to their digital fortune.

Investors are finding that the system's high-security makes it easy for them to get locked out.

Currently there are more than 3 million bitcoins that have been lost, according to blockchain tracking company Chainalysis. Since bitcoin was created in a way that makes its supply finite, that means that 14 percent of the currency could be gone for good.

"All the hackers in the world are targeting cryptocurrencies."
-Eric Larcheveque, CEO of cryptocurrency security company Ledger Wallet

What are the safety measures to prevent Bitcoin from going up in the smoke?