I have two antminers and I make about .01 BTC each with multipool. Bitcoin is usually the most profitable. On the
https://www.multipool.us/ homepage they show recent profitability. Also coinwarz.com has a good conparison on profitable coins. The difficulty with ASICs keep moving upward in sha256, but GPUs in Scrypt, or soon to be Scrypt-n have a more steady difficulty with steady payouts