design asic miner which do not use random numbers to crack the blockchain, use asic miners which use a modified chip which uses specific numbers (algotythms)
Algorithms (e.g. SHA-512) are sets of instructions. Their inputs are numbers. The algorithms themselves are not those numbers, so changing those numbers will not further your goal... unless someone has found an efficient method of converting SHA-512 hashes into useful protein folding information, which I highly doubt.
To be overly allegorical:
If I told you (the ASIC) to paint fences (the algorithm) and gave you a bucket of paint to do it with (the "numbers", the input), and you go and paint the fence for me (generate hashes)... what kind of paint would I need to give you so that you end up with a Mercedes (folded protein info) instead of a painted fence (a SHA hash)?
[And the answer is, of course, that I need to tell you to build cars instead of painting fences. I can't do this by changing the paint (the 'numbers') alone]
