This is already a classic and shabby story about someone who doesn't really believe in crypto, but if there was an instrument that would allow him to buy in the morning and sell in the evening without any worries about fees, transactions and security - then crypto would be very interesting asset. But that's the way big investors think, they don't necessarily understand or love something they make a profit on, but they want that investment to have a very easy entry and exit point.
That's true for most people who got involved with Bitcoin in the past 7-8 years.
The proof in favor of this is precisely in the fact that O'Leary talks about "the top 7 cryptocurrencies" because that way the profit would be much higher than if only BTC was traded. So there is no doubt that they want to invest, but they need something like an ETF and even more regulation, and it is only a matter of time before that happens.
Only during a major bull run and if you get lucky picking the right altcoins. Most of the time it's better to just stick to BTC,
especially if one doesn't have the time or energy to follow what's going on with altcoins.
I remember that thread and can see that I've upvoted some comments there, but the video is down.