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Author Topic: Devcoin Cancer Treatment Fund  (Read 1145 times)
FinShaggy
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May 25, 2013, 02:31:52 PM
 #21

So you're going to grow weed and then say it's sponsored by DevCoin. ._.

Even if it is good for treating cancer, I don't think that's the best advertisement, lol.

I think it's good advertising.
You know they have Cannabis rallies in about every state that have HUGE attendance, and same in Canada and the UK.

Plus, if we can document curing people that is good for MJ and DVC on an international level. And it actually makes the "drug user"/"silk road" side of Bitcoin look a little better.

If everyone is thinking outside the box, there is a new box.
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May 25, 2013, 06:41:20 PM
 #22

Also,

As soon as I get paid for writing on Devtome in June, I will be making an invention that cuts down on 2nd hand smoke Smiley
I've already made and tested the prototype Smiley

The invention will be open source, and a tutorial of how to make it yourself will be on YouTube.

If everyone is thinking outside the box, there is a new box.
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May 27, 2013, 08:33:10 PM
 #23



Thought this was relevant :p

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jimhsu
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May 27, 2013, 08:41:24 PM
 #24

Of relevance:

Quote
"The thing people forget is that killing cancer is easy. Radiation, drugs, heat, cold, thumping it with lasers or ultrasonics or a baseball bast, it's just another cell and those things can't put up much of a fight against SCIENCE. The problem isn't wiping out the tumours, it's the NOT killing everything they're attached to - healthy human cells which are unfortunately even more fragile. People have this vision of cancer as a multi-headed chimeric hydra, a diabolical monster rearing over a small doctor armed only with a scalpel. The reality is a lumberjack trying to kill one red ant among a thousand black ones he can't touch, and he's only got a sledgehammer, napalm and an ICBM missile to do it with."
~ Luke McKinney

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"All things are poison, and nothing is without poison; only the dose permits something not to be poisonous."
~ Paracelsus

Molecular biologist by trade. Heard of the effects of cannabinoids, but as always double blinded RCT evidence is lacking. There had been a few studies looking at the effects against CINV (chemotherapy induced nausea/vomiting) though, have to look them up.

"Trust, but verify."
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jimhsu
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May 27, 2013, 08:46:55 PM
 #25

Here we go:

Tramèr et al, Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review.  BMJ 2001; 323 doi: http://dx.doi.org/10.1136/bmj.323.7303.16 (Published 7 July 2001)
http://www.bmj.com/content/323/7303/16

Objective: To quantify the antiemetic efficacy and adverse effects of cannabis used for sickness induced by chemotherapy.

Design: Systematic review.

Data sources: Systematic search (Medline, Embase, Cochrane library, bibliographies), any language, to August 2000.

Studies: 30 randomised comparisons of cannabis with placebo or antiemetics from which dichotomous data on efficacy and harm were available (1366 patients). Oral nabilone, oral dronabinol (tetrahydrocannabinol), and intramuscular levonantradol were tested. No cannabis was smoked. Follow up lasted 24 hours.

Results: Cannabinoids were more effective antiemetics than prochlorperazine, metoclopramide, chlorpromazine, thiethylperazine, haloperidol, domperidone, or alizapride: relative risk 1.38 (95% confidence interval 1.18 to 1.62), number needed to treat 6 for complete control of nausea; 1.28 (1.08 to 1.51), NNT 8 for complete control of vomiting. Cannabinoids were not more effective in patients receiving very low or very high emetogenic chemotherapy. In crossover trials, patients preferred cannabinoids for future chemotherapy cycles: 2.39 (2.05 to 2.78), NNT 3. Some potentially beneficial side effects occurred more often with cannabinoids: “high” 10.6 (6.86 to 16.5), NNT 3; sedation or drowsiness 1.66 (1.46 to 1.89), NNT 5; euphoria 12.5 (3.00 to 52.1), NNT 7. Harmful side effects also occurred more often with cannabinoids: dizziness 2.97 (2.31 to 3.83), NNT 3; dysphoria or depression 8.06 (3.38 to 19.2), NNT 8; hallucinations 6.10 (2.41 to 15.4), NNT 17; paranoia 8.58 (6.38 to 11.5), NNT 20; and arterial hypotension 2.23 (1.75 to 2.83), NNT 7. Patients given cannabinoids were more likely to withdraw due to side effects 4.67 (3.07 to 7.09), NNT 11.

Conclusions: In selected patients, the cannabinoids tested in these trials may be useful as mood enhancing adjuvants for controlling chemotherapy related sickness. Potentially serious adverse effects, even when taken short term orally or intramuscularly, are likely to limit their widespread use.

---

Jatoi et al. Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study. JCO January 15, 2002 vol. 20 no. 2 567-573
http://jco.ascopubs.org/content/20/2/567

PURPOSE: To determine whether dronabinol administered alone or with megestrol acetate was more, less, or equal in efficacy to single-agent megestrol acetate for palliating cancer-associated anorexia.

PATIENTS AND METHODS: Four hundred sixty-nine assessable advanced cancer patients were randomized to (1) oral megestrol acetate 800 mg/d liquid suspension plus placebo, (2) oral dronabinol 2.5 mg twice a day plus placebo, or (3) both agents. Eligible patients acknowledged that loss of appetite or weight was a problem and reported the loss of 5 pounds or more during 2 months and/or a daily intake of less than 20 calories/kg of body weight.

RESULTS: Groups were comparable at baseline in age, sex, tumor type, weight loss, and performance status. A greater percentage of megestrol acetate-treated patients reported appetite improvement and weight gain compared with dronabinol-treated patients: 75% versus 49% (P = .0001) for appetite and 11% versus 3% (P = .02) for ≥ 10% baseline weight gain. Combination treatment resulted in no significant differences in appetite or weight compared with megestrol acetate alone. The Functional Assessment of Anorexia/Cachexia Therapy questionnaire, which emphasizes anorexia-related questions, demonstrated an improvement in quality of life (QOL) among megestrol acetate–treated and combination-treated patients. The single-item Uniscale, a global QOL instrument, found comparable scores. Toxicity was also comparable, with the exception of an increased incidence of impotence among men who received megestrol acetate.

CONCLUSION: In the doses and schedules we studied, megestrol acetate provided superior anorexia palliation among advanced cancer patients compared with dronabinol alone. Combination therapy did not appear to confer additional benefit. 


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FinShaggy
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May 27, 2013, 10:54:53 PM
 #26



Thought this was relevant :p

Not in a petri dish. LOOK UP RICK SIMPSON. Cannabis cures tumors and cancers IN HUMANS Smiley

If everyone is thinking outside the box, there is a new box.
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