There's plenty of distributed computing projects, so I'm sure you could find one you are willing support morally or ethically. Folding@Home is an easy one to get behind, there's SETI@Home if your interest is Aliens
None of them will pay you for your GPU work, though, so it's just a warm fuzzy feeling you'll be getting (that actually may be the heat from the GPUs, though) along with an electric bill.
Alt coins aren't dead, why not bother with them? Why not run an internet cafe that runs LTC scrypts when not in use? Should be pretty damn simple to setup, especially with all the software they have out there now for administering sites such as internet/LAN cafes.