The bitcoin client really needs some encryption and a welcoming pdf that opens up automatically, with some basic information on where the wallet is, how to encrypt it, and perhaps functions like loading a wallet from a USB stick. I encrypt my files manually but know for a fact that most generation myspace/facebook people arent doing this.
Chances are that most people across Africa will be using mobile phones to access their bitcoins and the web, not laptops or PCs.
Just as most Africans by-passed owning a landline and went directly to owning a mobile phone, most of them have also never owned a laptop or PC before getting access to the web via their phones, and probably never will.
Also, with many Africans (particularly in Kenya and other parts of East Africa) already used to mobile phone payment systems like MPESA, bitcoin could take off quite significantly and spread more rapidly throughout the African continent than in Western countries.