Has anyone done some calculations? What is the profitability estimate in BTC for 1 scrypt MH?
I haven't done any profitability calculations myself (yet). If you / someone is going to keep in mind that the way p2pool works it takes a bit of time for the payouts to ramp up to their full payouts. At the point you stop mining on the pools there will still be payouts, decreasing of course. This is inherent for p2pool to prevent pool hopping.
With the merged capabilities when you point 1 mh/sec to, for example, the ekrona pool you're pointing 1 mh to ekrona, 1 mh to org, 1 mh to peseta and 1 mh to burbu. In effect it's like having 4 rigs that put out 1 mh/sec each and pointing them to 4 different coins. Efficiency of your rig is allot higher with the merged mining aspect.
Another aspect / problem is that the pools are still young and with some of the merged coins having a somewhat high difficulty we're more or less depending on luck to find a block on them (peseta is a good example, allot of network hashrate and our hashrate is a drop of water in the big bucket). For ORG and Burbu coin we're seeing regular blocks coming by, peseta is more or less based on luck at the moment due to our low hashrate compared to the network hashrate.
Keep in mind though that merged mining on scrypt is rather new and the coins that support it are relatively new as well, some of them might not even be on main stream exchanges (yet)