Crawford has much more experience, better score, more to lose. Madrimov is still a newcomer when it comes to pro fights.
IMO Crawford is going to be very well prepared and harder to counter since he's a southpaw and you don't get a lot of good sparing opponents who excel in this stance, so Madrimov is going to have much less experience in fighting southpaws than Crawford vs orthodox fighters.
Whatever Madrimov does in the ring Crawford is ready for that, you're not an elite if you do not have multiple plans or the ability to shift in the fight, after the Spence fight I consider Crawford a flawless fighter, can you imagine a fighter who was considered his co-equal getting knockdown by his jab.
Madrimov is not better than Spence so we can conclude that it will be a much easier fight for Crawford, Crawford needs to fight level-A fighters now after the Spence fight fighting other unknown names is not attractive anymore, so I expect him to fight any of the Charlo or Canelo, so let's see.