It is possible that a transaction malleability bug with Gox was used very slowly with small amounts and massive numbers of accounts over time in order to avoid drawing any attention until it was too late.
Two guys at MIT looked at the relevant logs and concluded that most attempts to exploit the "malelability bug" came only after Mark blamed it for the loss; and at most a couple hundred BTC could have been lost that way:
http://www.technologyreview.com/view/526161/the-troubling-holes-in-mtgoxs-account-of-how-it-lost-600-million-in-bitcoins/IUnfortunately, because of a likely gag order, Mark is unable to confirm or deny any of this, even though the gag order probably has more to do with money-laundering than a Gox heist itself.
Like the malelability bug, the gag order may be only an excuse. But he surely must have been advised by his lawyers to keep his mouth firmly shut. That is standard legal advice for anyone in his situation.
If other people are involved, with or without his cumplicity, perhaps he is silent for fear of physical consequences. Someone who steals such a large sum will have the motivation and the means to murder anyone who threatens his loot and freedom. (Note, for example, that Ross Ulbricht is charged with trying to hire a hitman to take out someone who was blackmailing him; whether it is true or not, it is quite plausible.)
It is hard to understand how he could have, all alone, made the coins vanish so completely that the crowd detectives still cannot locate them in the blockchain, even with the help of the leaked database.
Autumn's death might have just been a result of her having put a client's funds too heavily into Gox. Something like
one of these. Was there a note or anything? I guess I never heard if there was a note. While it might seem "fun" to speculate on this stuff, keep in mind that she did have family and friends that aren't likely to want to talk about it, let alone hear people debate about it.
As far as I know, there was no note or any other evidence clearly indicating a suicide, nor any specific cause. Someone who was close to her implied that she was somewhat "down" on the previous day, but nothing specific. Brock Pierce later called her friends for an evening of remembrance or something in Los Angeles. I have not read anything coming from her family about possible reasons for her death.
I find it hard to believe that she would kill herself for advising someone to put money into MtGOX. She was hardly alone in making that mistake, and every investment advice has at least 50% chance of being disastrous
. Although she was involved with virtual currencies in general, AFAIK she was not really a "bitcoin evangelist" that would push reluctant investors into bitcoin.