You probably don't need them to be connected to one physical PC. Instead, have them plotted in a way that they do not overlap, and have them all using your same BURST-address.

I currently have to boxes mining to the same account, so I cannot see why you couldn't have each machine mining with it's hard drive instead. Of course, the drawback is that you would have multiple boxes and higher electrical costs by doing so.

Another option would be stripping out the drives and connecting as many as possible to your motherboard and/or via USB3 hubs to one or more computers.

yeah start mining now!

what were u thinking, you already own those 27x 1TB drive!, it does not look you need to invest something other than your time and effort, mining cost will be ~200 watt / hour (assuming each drive consuming 5 watt, and other pc component about 70watt), for 0.15$/kwh electric cost it would be 0.72$ per day (not even one dollar)

I think i saw this thread somewhere else : https://bitcointalk.org/index.php?topic=837345.0

lol , good luck of copying my thread

USB miner? Cmon, its not worth it even with free electricity..

You need to set up a full node. Basically you will run your own pool. If you can't be bothered, use ck's pool. It's designed as a fall back or for solo miners.

I have a topic about this and solo minning on old equipment, there are solo pools out there where you get all 25 btc (so it's simple to do) and 4 usb miners would be like 20w so why not?

No.  It is almost impossible.   

You can do it, but it would be like trying to win the lotto.

they where pretty much the first form of USB ASIC that avrage jo could afford i think they first came out at 2BTC each and could surpass even the most overclocked GPUs around at the time

today there just a collector or novelty item on here they rarely sell for more than 0.001 but on ebay people still pay 0.05 for them