Depends what you mean by it, 100x in 10 years or 100x in 1 year? The time frame is different, for a relatively new coin it would not take as much time to 100x compared to a coin in top 15. But honestly it is getting harder everyday, more and more projects everyday, which is not good, too many coins, the competition is huge now, if you can find a good coin that can 100x then tell me about it, but I don't think there are any.
Take a look at Nullex, I think it can, what is your opinion?