Hi,
If someone hacks my computer or cloud and they would steal my wallet.dat file. will that person be able to build up my wallet on another computer and steal my coins when my local wallet is still up and running on my computer?
You should be safe in the cloud, but if a hacker gets inside your computer and monitor your keystrokes, no amount of encryption will help you as he will be able to catch you typing the password through a keylogger. Therefore, isolation is needed for maximun security (cold wallet).
I would only bother if you had a decent amount of BTC, otherwise, encryption + firewall and AV if Windows user, should be enough.