I would like to see Amazon and eBay accept Bitcoin. I'd be buying a lot more stuff there.
For both companies it would be a huge benefit: Amazon would no longer suffer from chargebacks or fraudulent payments. And eBay could setup an escrow-alike payment system, where the buyer sends coins to eBay, seller gets confirmation from eBay that funds have been paid and he ships the goods (with track & trace), buyer confirms receiving them, and seller gets the coins (minus 0.3% eBay fee).
Also, I would certainly buy games, music and movies with BTC if they were available (and reasonably priced).
And I want Wikipedia to accept Bitcoin donations. Free information should be funded by free money (free as in speech, not as in beer).
If this happened the price of bitcoin would absolutely explode!