PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
PANIC: fatal region error detected; run recovery
DB_LOGC->get: LSN: 1384/5911106: read: DB_RUNRECOVERY: Fatal error, run database recovery
DB_TXN->abort: log undo failed for LSN: 1384 5911106: DB_RUNRECOVERY: Fatal error, run database recovery
PANIC: DB_RUNRECOVERY: Fatal error, run database recovery
PANIC: DB_RUNRECOVERY: Fatal error, run database recovery
PANIC: fatal region error detected; run recovery
That appears to be a database error.
I would backup my wallet file (you should have backups already) then move the data directory elsewhere while the program is closed and redownload it all from the beginning then copy the old wallet back into place and restart the client. That's just how I'd approach it.
Maybe someone else in here can give you better advice on repairing the db, I'm not sure if / how that can be done.