"Single Rail"! Make sure it's a Single Rail PSU! I've owned many computers, but only once has a PSU ever failed. And that was because I overloaded a rail on one of my PSU's. Made a load pop, some smoke shot out the back, and then a very load electrical buzzing for a quick second until the breaker blew. Luckily, it didn't fry the rest of the mining rig.
You technically can do a multi-rail, as long as you load balance properly. I had a 1000W 4 rail unit, that ran 3 smaller cards just fine. It wasn't until I tried to run some 5970s that the rails started giving me fits.