This should be sticky, I have been reading of too many cases of loss of funds. For anything more than daily change, hardware wallets are a no brainer. This article is why:
http://betbybitcoin.com/protecting-your-bitcoin-holdings-betbybitcoin-special/This article is exclusive, but the information it contains is so important and while I spend so much time emphasizing security here, I feel it is a must to follow this advice.
If anyone does wish to buy a hardware wallet, do use the link in my sig
As I do get commission for it. I do not expect any donations but if your going to order one anyway I wouldn't say no to a commissioned sale!
Please, please give this a read and make up your own minds. I have presented hyperlinks of real situations in this article. It is so important. The cheapest Hardware wallet is less than £20, coinbase multi sig vault is FREE minus one or more paper printouts of the shared and user key. It is worth the investment. And not just limited to Bitcoin.