There is no universal receipe for managing bitcoin, everyone has its own preferences. But I would say that the best way it's to split the coins for different purposes, like investing/trading, saving and using for the daily purposes. And the main goal is to enlarge your portfolio at the end.
that's better knowing how to keep it properly and maximize the benefits, if you know how to do your research there's some particular way to keep it
and manage it properly everything is here just need to read some thread and carefully understand and you will find the best way.