Not anytime soon. Somebody has to develop a user friendly interface to it. I mean a web service with a top notch UI.
Also multi sig transaction is not an escrow as such. You still need both the buyer and seller to agree to release the coins or else they are lost forever. Even after the buyer makes payment the seller could demand extra money to release the bitcoins.
With a third party escrow the seller can't do anything like that. The escrow agent can use his own judgement and release payment if he is shown proof that the buyer made payment.
I agree with all of it, but multisig would somehow remian useful. Consider, for example, a platform like Silk Road where credit rating is quite important and buyers have to escrow their funds with the platform, since the identity of the platform operator is not known, there is always the risk that the operator will run away with the escrowed money. Now with the multisig any malicious buyer will be punished by the rating system, and the escrowing address can be used as proof, in this case a huamn escrower would not do better at judging the proof of delivery from the buyer as there will be none.