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Author Topic: [ANN][PRESALE] Zenome.io - decentralized genome economy. Reveal your DNA value.  (Read 4297 times)
Zenome Platform
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September 19, 2017, 01:13:20 PM
 #1

 ZNA, The Zenome Platform token.
blockchain-based genomic ecosystem

   The “Zenome” name is a portmanteau that fuses words “zen” and “genome”.



Genes have a profound impact on person's health and lifestyle. Recently many discoveries of genetic factors connected to longevity, overweight, sports success, drugs susceptibility and other traits have been reported. These findings provide opportunities for different kinds of genetic services.

Disease treatment
Genetics provides better understanding of disease mechanisms and drives the development of an effective treatment. It's possible to predict what disorders a person is likely to develop and prevent future complications.
Disease prevention
Prospective parents can undergo genetic testing to determine the risk of having a child with a genetic disease. In the high risk cases the assisted reproductive technology is used to ensure that the baby will be free of the disease under consideration.
Advice for lifestyle change
Lifestyle modification and personalized nutrition based on a genetic profile of an individual could greatly improve the quality of life and life expectancy. Not to mention genetic services utilizing genetic profile to give recommendations for better athletic performance and weight loss.
Genetics for Fun
"Recreational" genetic testing: Ancestry, DNA-Based Dating.

Your DNA is an Asset
Zenome is the Market


 How Genetic Services are Provided For Now
   Or the Overview of Challenges and Disparities in Genomics

The highly promising market for genetic technologies is growing rapidly. The advent of next-generation sequencing technologies has resulted in a significant drop in prices for genome analyzing and an exponential increase in available genomic data.

To store such a large amount of genomic data, special genomic databases have been created, financed by governments or large corporations. These databases contain clinically relevant information as well as the relationships between genetic traits and diseases.

Impact on Science and Society
The development of genomics has led to the transformation of biology, agriculture, medicine, social sciences and many other sciences.

 Google, Apple, IBM and a number of commercial companies have set the objective of using genomics to adjust their products and services according to the customers' genomic profiles. This led to rethinking of the notion of privacy.


Currently, the total market volume is about approximately $25 billion.


But some serious challenges for genomics still exist, concerning availability, privacy and ethics.

Genetic Privacy
DNA is a molecule where all genetic information is stored. This information is closely connected to personal and group identity. That means that genetic privacy has a value on its own, and genetic privacy protection is of great importance for a meaningful life.
Genetic discrimination
Discoveries in genetics have opened the door to new notions of discrimination. Genetic discrimination occurs when people are treated differently by their employer or insurance company because of a specific gene mutation.
Undermined privacy as a price for participation in open reseach
Informed consent is a key issue in every biomedical research study that means that participants understand the consequences and agree with the terms of the research study, which may include giving permission to use the data in future projects.

As a result of privacy-related concerns overly complicated legal limitations took place in many developed countries.

Genomic Data Monopolization
The majority of genomic data is hosted in developed countries in databases controlled by corporations and governments. Access for the scientific community is limited by commercial subscriptions or restricted. In many cases research groups should provide explanations of how the research will contribute to the public good and wait months for approval.
Pseudonimity of Data stored in genetic databases
Although the founders of genomic databases claim they securely and anonymously store genomic data, in reality, the data stored are only pseudonymous, as in some cases, individuals have been identified based on their genomic information.
Low Awareness
Public awareness of genomic medicine remains quite low in the developed and even worse in developing countries. That means that people, in general, have little understanding about possible benefits of genomics as well as possible dangers associated with it.


Monopolization of genomic data inhibits further scientific progress.

Zenome project

The Zenome Platform is going to raise awareness on genomic medicine, so users can make conscious decisions regarding their data.
To ensure that, the Zenome Platform is based on the following fundamental principles.


Individual ownership of personal genomic information
    User has all rights for personal genomic data.
Freedom of choice
    User decides how genetic information should be used.
The right to share
    User may grant access to genetic data to a third party in a way restricting data copying.
Privacy
    Encryption prohibits access to genetic data without an explicit user's permission.

System Architecture
Simply put, Zenome platform is a P2P network. Some nodes are resource providers that store and process genetic information. Participants, analysts and service providers connect to distributed network and interact with each other. Data exchange is secured through encryption and utilization of blockchain smart contracts.

  Zenome platform main actors:
  • Resource provider provides storage and CPU/GPU power for a reward.
  • Participant uploads individual genetic data, gets reports and possibly uses genetic services.
  • Analyst works with genetic information (a data scientist or a scientific organization)
  • Service Provider implements a user-space genetic service (possibly paid) on the platform.

Distributed data storage provides high availability and fault tolerance through replication and scale out ability.
Distributed data processing enables any user to become a node by providing disk space and CPU/GPU time to the network.
Service Provider API is designed to ensure maximum confidentiality. User sees what data is to be transfered and has to explicitly confirm data exchange.
Decentralized economics is powered by the utility token of the platform, Zenome DNA Token (ZNA).

Genome Tokenomics
It appears that the exchange of genetic information is of crucial importance. The prospective genetic market must ensure protection from possible misuse and genetic discrimination in particular. It is particularly important to maintain transparency and equal access to this market.

Zenome aims at creating the personal genomics infrastructure, that would enable participants to:
  • Upload genetic information and take control of it.
  • Securely store own genetic information.
  • Make profit by selling access to genetic data or part of it.
  • Undergo genetic testing in exchange to the right to use genetic information.
  • Get individual dietary recommendations or personal training program based on genetic makeup.
  • Make use of other genetic services.
The principal customers of genetic information are companies interested in genetic targeting such as Google, Facebook, Unilever and pharmaceutical companies.
Inside Zenome Platform different types of information are inextricably intertwined. The nature of each type determines the way to store information of that kind.
    Financial data, which includes records of transactions, is stored on blockchain.
    Anonymized genomic data is stored on the distributed network.
    Participant's personal data is kept on their own computers only.
Treating data of different kind differently provides privacy as well as scalability of the system.

Since all data transactions, including buying and selling data, are governed by smart-contracts, interactions can only include balances stored on blockchains.

Using any of pre-existing tokens for this purpose would result in unreasonable dependence on the valuation of external token. Thus, a separate utility token should be issued to power economic interactions on the platform.

Utility Token
A platform's utility token, ZNA (Zenome DNA Token), powers Zenome's decentralized economics. The token is used as an exchange unit in the internal ecosystem. Value of ZNA depends directly on the success of the platform.

ZNA is an utility token: ZNA is not evidence of ownership or right to control.

Tokens will be allocated during the crowdfunding period.
Crowdfunding consists of:
  • Presale: tokens will be distributed among early contributors at fixed price;
  • Sale: During sale tokens will be distributed among others at dynamic price;
  • Post-sale emission: additional token pools will be allocated: Team, Fund, Marketing tokens, and Frozen tokens (gradually unlocked during a 5 year period after 10x valuation growth).
Limited Supply: no new tokens will be created afterwards;

Presale Details:
Funding cap: 3.2m ZNA
Bonus 25% for all if funding cap is reached.
Accepted: ETH only
Exchange Rate: 0.3$ per ZNA
Duration: 7 days                                            
Sale Details:
Security hard cap: 100M$
Hidden cap: Yes
Bonus x2 for the hitting a hidden cap.
Accepted: ETH, BTC, ...
Duration: 14 days
Exchange Rate: Dynamic
  ExchangeRate = 0.6+α·TokensSold
  α = 3.2·10-8 $/ZNA
An example of possible Dynamic Exchange rate function.
It may change and will be fixed before the pre sale starts.            
Postsale Allocation:
Let R to be a total amount of tokens sold during presale and sale.
After the sales additional token will be emitted for different purposes:
    Zenome Foundation: 0.26·R  (instantly)
    Marketing: 0.04·R  (instantly)
    Zenome Team: 0.2·R (vesting)
    Frozen Tokens: 2.5·R (locked by a smart contract)
Frozen tokens (details):
Basically, Frozen Tokens are tokens sent to a smart contract that locks them until a condition (10x valuation growth) is met. When condition is met, tokens are distributed gradually during a 5 year period as long term incentives.
Vesting
Team tokens are subject to a 3 years vesting schedule with 6 months cliff. Vesting schedule is written into the smart contract and cannot be manipulated in any way.

Follow us
Dear community, we kindly invite you to read our White Paper to learn more about Zenome project. We will appreciate to get your insights and feedback on this subject.


Join our community now to be a part of genetic revolution tomorrow. Should you have any questions regarding Zenome platform, don’t hesitate to contact us primarily on Telegram and Facebook.
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September 19, 2017, 01:21:29 PM
 #2

RESERVED
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September 19, 2017, 01:24:52 PM
 #3

How do you plan on making money? I mean, how is the token going to generate value?

The importance and possibilities of genetics are obvious, but not so your business model.

ICOs:  FidentiaX
MiniApps
        Binary Options:  Olymp Trade
BitPlutos

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September 19, 2017, 01:34:47 PM
 #4

Reserved Indonesia translation.

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September 19, 2017, 02:07:19 PM
 #5

How do you plan on making money? I mean, how is the token going to generate value?

The importance and possibilities of genetics are obvious, but not so your business model.

Good question actually! Huh

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September 19, 2017, 09:02:13 PM
 #6

How do you plan on making money? I mean, how is the token going to generate value?

The importance and possibilities of genetics are obvious, but not so your business model.

Good question actually! Huh

Really. Very cool project in fact, but you need to understand how it will stay afloat financially. And the concept itself - I like it. I will support the project if I am confident in it.

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  TRADE.IO       ║     WHITEPAPER  •  ANN THREAD  •  TELEGRAM     ║     JOIN THE TRADING REVOLUTION
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September 19, 2017, 09:44:35 PM
 #7

Reserved german translation.
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September 19, 2017, 09:48:10 PM
 #8

Reserved Hindi translation

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September 19, 2017, 11:30:24 PM
 #9

very good logo zenome, unfortunately there is no picture that describes your project in this annoucment, because the picture can explain more detail information and attract the attention of reader  Smiley

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September 21, 2017, 01:31:11 PM
 #10

How do you plan on making money? I mean, how is the token going to generate value?

The importance and possibilities of genetics are obvious, but not so your business model.
Thanks for the feedback. We have updated the opening post.

In short, Zenome platform will provide infrastructure for genetic data exchange.
The basic premises are:
1) Everyone has rights over individual genomic data.
2) Many companies are interested in getting these data for different purposes.
3) Privacy should be ensured as much as possible.
4) User should make an informed decision. The platform should warn user about data exchanges that can compromise user's privacy.

So let me give you some examples:
Example 1
Some company wants to apply genomics to improve a service/a product. (That could be a personalized nutrition service, for example.)

The company needs 10 000 records, each containing information about ~20 SNPs, to conduct a research.
So company makes an offer to buy this tiny part of genetic information and sets a price. The offer then propagates in our network.

Each user who has the data gets notified. The user opens the offer and sees all the details, including price and the system message "Privacy won't be compromised by sharing that little data." Then user may accept and get reward or decline an offer.


Example 2
The research group in a large corporation is developing a new promising drug. And there is a need for genome-wide association study of more than 1000 SNPs.

So the research group make an offer from their corporate account. Users get notified as well, but this time they will see a warning: "Attention! Privacy can be compromised!". Then go some details: "Attention! Genetic Identification possible!" and "Consider reading about the corporation (link is given) before accepting the offer." Once again user may accept and get (much larger) reward or decline an offer.


So the Zenome is a genomic market, but the platform is designed to ensure users' awareness. If a particular exchange can compromise privacy, the platform will explicitly warn user.
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September 21, 2017, 02:04:22 PM
 #11

Really. Very cool project in fact, but you need to understand how it will stay afloat financially. And the concept itself - I like it. I will support the project if I am confident in it.

Concerning financial aspects, there is another use case.
Companies that provide genetic services can deploy their (paid) services on the platform.
That could be a genetic dating service, or a cosmetology recommendations service.
Each user can access any service and spend tokens on paid features.


Different service providers using the same API on the Zenome platform would eventually
create an integrated environment and provide a consistent user experience.
Also, there
is no need for an additional account for each service. No need to undergo genetic testing
once more. User just should give access to genetic data that user already has.

This greatly simplifies the use of genetic services and we expect them to be used more.
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October 02, 2017, 11:10:53 AM
 #12

Join our community now to be a part of genetic revolution tomorrow. Should you have any questions regarding Zenome platform, don’t hesitate to contact us primarily:
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October 02, 2017, 01:23:40 PM
 #13

Good luck guys! Your projects sounds really interesting.
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October 02, 2017, 02:49:44 PM
 #14

Good luck guys! Your projects sounds really interesting.
Thank you!
If you have any questions - please don’t hesitate to contact us primarily on Telegram and Facebook.
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October 03, 2017, 02:20:04 PM
 #15

How do you plan on making money? I mean, how is the token going to generate value?

The importance and possibilities of genetics are obvious, but not so your business model.

Boi, do you even know much Genomic companies make every year?

I like the idea and the concept. Wish you good luck guys!
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October 03, 2017, 02:23:17 PM
 #16

What exactly is the business plan for Zenome, what are the ICO funds for, and what are your legal barriers that you need to conquer / in what country are you planning to operate first?

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October 03, 2017, 02:32:46 PM
 #17

hi
theirs not much about the team at all
most other projects have respected business people on board
do you have any PHD's in biology/genomics working with you guys
or is all business guys?

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October 04, 2017, 10:33:22 AM
 #18

hi
theirs not much about the team at all
most other projects have respected business people on board
do you have any PHD's in biology/genomics working with you guys
or is all business guys?

The zenome.io team is working in the field of genetics and Molecular Biology since 2009. We have experience in conducting academic studies as well as in practical applications. Starting from 2012, we have been developing a personal genetic diagnostic system, featuring the novel approaches for individual genetic analysis and estimating the influence genetic factors have on observable traits.

In 2015 we have received funding assistance from the «Skoltech Translational Research and Innovation Program»  set up under the  Center for Entrepreneurship and Innovation  of Skoltech. Our studies were published in leading scientific journals: Genes Development, Nucleic Acid Research, BMC Genomics, Molecular Biology and Evolution, Biochemistry, Epigenetics and others.


Let me introduce our Zenome team to you Smiley

Alexey Gorbachev
Role in the Project: Founder, business

- Moscow State University, department of molecular biology (MSU)

- Ph.D. in molecular biology and biochemistry
 (https://scholar.google.ru/citations?user=yR93FTUAAAAJ&hl=ru)

- Molecular biologist and Blockchain Enthusiast
Specialist in molecular biology and personal genomics.
Alexey has a significant scientific background, expertise in business, and project management. In Zenome Alexey is responsible for the overall vision and development of the business.


alex@zenome.io

Nikolay Kulemin
Role in the Project: Founder, bioinformatics

-Moscow Institute of Physics and Technology, department of molecular and biological physics (MIPT)

- Ph.D. in bioinformatics
https://scholar.google.ru/citations?user=Ji1O1m4AAAAJ&hl=ru

- Bioinformatist
Specialist in bioinformatics and mathematical biology, has experience of academic research and applied developments in the genome industry. Nikolay is a founder of a company developing new algorithms for genomic analysis.

https://www.linkedin.com/in/nikolay-kulemin-50ab47a9/

nick@zenome.io

Vladimir Naumov
Role in the Project: Genomic data scientist

- Pirogov Russian National
Research Medical University
(RNRMU)

- Data scientist in human genomics
Bioinformatics and data analysis specialist. ex-CSO at iBinom, bioinformatics scientist at GERO, 8 years in genomics industry. Works on creating pipelines and developing new ways in analysis and visualisations of genomic data.
https://scholar.google.ru/citations?user=aHkS2yIAAAAJ&hl=ru
 
https://www.linkedin.com/in/vladimir-naumov-8285a25b/

vov@zenome.io

Sergey Popov
Role in the Project: Smart-blockchain developer
- Moscow Institute of Physics and Technology, department of general and applied physics (MIPT)
   
- Theoretical physics, theoretical informatics and pure mathematics
Distributed systems architect, smart blockchain developer
Blockchain, P2P, distributed systems
sp@zenome.io


Dmitry Kwon
Role in the Project: Advisor
- Moscow State University, department of molecular biology (MSU)
Ph.D. in molecular biology

- Molecular biologist, business development manager
Specialist in molecular genetics. Dmitry has a significant scientific background, expertise genetic analysis technologies, genomic and diagnostic markets, has successful business experience in biotechnology and Dx top intl companies.

https://www.linkedin.com/in/dmitry-kwon-2763b119/

dk@zenome.io
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October 04, 2017, 11:37:40 PM
 #19

i have to admit this can be a very interesting project if manages to convince people that the personal data and genetic resources can be used like this.

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October 04, 2017, 11:45:39 PM
 #20

very few people interacted with this thread up until now

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