Somebody tested mainboard Asus B250 with window 10 (look at the mainboard layout for your references) and dont forget to make power as A-B-C carefully, it could recognize up to 16 GPUs P106-100 and each achieved hashrate at ~25Mh/s, total around 403 Mh/s, too good to be true!
Updated: Now we are successful on setting 21 GPUs on Asus B250, setup: Core i3-7100, 8 Gb RAM, 32 Gb Virtual Memory (for >16 GPUs, need more than 16 Gb Virtual Mem). Riser's requirement is not that much, just use the cheapest PCIE 1 to 4 extender.