Thank you all for the responses.
Since posting I have done more research and settled in on a complete new build taking only my EVO SSD and MSI 1060 GTX
https://pcpartpicker.com/user/nazran/saved/2dTm8dThe Corsair 780T appears large enough and it has modular drive cages that can be removed in front of the intake fans. I will mount my SSD on the backside. I am going to water cool the Coffee Lake i5 8400 (None of the games I play... World of Warships, Tanks, Planes, Warthunder, Civ 6 are huge CPU users.) at first with a NZXT Kraken v42. The radiator is 120/140 mm fan size which I will play with mounting as a top exhaust. I figure this might take a few degrees of ambient temp out of the case.
I am going to try sandwiching the MSI GTX 1060 6GB between the 2 MSI GTX 1080 ti miners to start with and just see what the temps do. I did see an interesting fan modding idea that could put a 140mm fan right in front of the cards to force air between the card spaces.
I am also going to try to make it a work of art with the MSI Mystic Lighting RGB system and maybe even getting custom colored GPU cables.
If it doesn't work out I can always take the 1060 GTX out and put it in to my current rig and let that be the kids machine and I can use scheduled tasks and batch files to have it mine in the night.