I love Bitcoin-Qt to death because it's the one, the only, the original. Unfortunately it's not the fastest, the most efficient, or the most user-friendly.
As stan.distortion mentioned, MultiBit (
https://multibit.org/) is very quick to set up, and also easy to use. They added encryption of wallet files (very important for security) in April, so make sure you use version 0.5.9 or newer if you're going to try MultiBit. MultiBit supports multiple wallets, which is handy sometimes.
Electrum (
http://electrum.org/) is another good option. One of its coolest features is that it uses a deterministic wallet: your wallet is created from a seed, which you can use to "recover" (really recreate from scratch) your wallet if something goes catastrophically wrong and you lose your wallet file and backups.