Hi and thanks for your replies.
But I am pretty sure that it is bitcoin.exe - related, since I have tried 3 Harddrives already. That means when I
start bitcoin.exe on D: then D: start clicking and becomes frozen, when I shut down bitcoin.exe, everything goes back to normal
start bitcoin.exe on E: then E: start clicking and becomes frozen, when I shut down bitcoin.exe, everything goes back to normal
start bitcoin.exe on X: then X: start clicking and becomes frozen, when I shut down bitcoin.exe, everything goes back to normal
if it is not bitcoin.exe-related, that means all 3 harddrives are about to die and that is not very likely.
Are you sure these are three different *physical* hard drives? (And not just three partitions on one hard drive.)