I'm currently a user of MyCrypto (aka MEW) and never touched anything else. I want to know what are your thoughts on Mist and MetaMask? I'm not planning to use them for ETH only, I will be using ERC20 tokens too.
Metamask is also best ERC20 compatible wallet , it provides you extra layer of security from phishing sites. And in meta mask your private key never leaves from your chrome extension like private keys in nano ledger or trezor hardware wallet.
If for any reason you don't like meta mask interface , what you can do is connect metamask to mew and do transaction simply from MEW.
As you are already using MEW , you can import your wallet in metamask no need to create new.
And in meta mask you have to add new tokens manually by mentioning smart contract address , decimal symbol same as we usually do in MEW.
Regarding Mist I don't have any experience with it , so can't comment on it.