I think that Wells Fargo is seeing an opportunity to get involved with new technology before other banks are forced to. Wells Fargo has been in business since the 1800's. That is in part from being able to be "forward" in their thinking. They have fallen behind some of the other banks during the past decade. They are probably now realizing that they need to go back to their roots and start looking for ways to gain more ground again. I cheer them on for this and although I have not banked with them I would be thrilled to take business to them if they show that they are open to Bitcoin and begin to provide services for users. We will see what they decide to do though.
Bitcoin is to banking what torrents are to music and video industries... but that means it presents NEW opportunities if they are willing to adapt. The MPAA and RIAA continue to try to resist, while others embrace the new models. For Bitcoin, a bank could offer some services if they see it won't go away. For example, they can store your coins (for a fee) and even offer insurance on the deposit (similar to what they did in the UK just recently). They could also offer services to buy or sell coins, just as they do for foreign exchange currently. Why not? I mean, maybe a bitcoin loan doesn't make sense, but there are other opportunities to adapt. Dare I say it - resistance if futile!
Here's hoping they may look at the opportunities...