So what IS the most profitable coin and why?
=]
The reason why that's such a hard question to is because once everybody knows the correct answer, it then becomes the wrong answer
(When everyone starts mining a coin the difficulty goes up, not to mention the the price might dip because there'll probably be a lot of people looking to sell as quick as possible).
This is why multipools are really only good as your fallback pool - the best way to make money mining is to either research/pay attention to what's happening or pick a coin that you think will rise substantially in the future because you believe it is one of the lucky ones out of the hundreds of new coins out there that actually has a future.
Case in point - my 1.25Mh/s rig made about $100 in two days of mining USDe. Then the difficulty quadrupled, ending that cash cow.
(Look for a coin with a very active and enthusiastic community of users and developers)