2048^21 is impossible.
If one had a super fast GPU/FPGA rig, say 600MH/S, and assuming one potential combination equals one hash, by my calculations it should take 1.823e+53 years. I don't know how much value the OP had stored in the Trezor, but the cost of running that server for that long might not be a financially sound decision. And then there's the pesky theory that the sun will swallow the earth in a mere 4 billion years.