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As far as films, try producing Blazing Saddles today.
What a coincidence. I was watching that today on Netflix and thinking the same exact thing. I hope that our new uber sensitive culture will give us some decent entertainment. Look at the movies that have been coming out these last few years. So bland and "PC". The Last Jedi is a perfect example.
There are countless examples of the destruction of comedy.
It's ridiculous to assert that good alternative subjects will be found, as the "acceptable subjects" shrinks to one percent of yesterday's subjects.
The simple result is that comedy becomes less funny, or simply not funny.