That's bizarre. A couple of weeks ago I used Electrum to initialize my KeepKey, and had no issues. I don't use it as my main hardware wallet, but right now it's set up as a backup for my Trezors. In an effort to help you out I just tried to access it using Electrum, and could not. The KeepKey chrome extension didn't have any problem accessing the wallet (which is kind of useless because that only works for p2pkh adresses.)
When I tried with Electrum I got this message:
No hardware device detected.
To trigger a rescan, press 'Next'.
If your device is not detected on Windows, go to "Settings", "Devices", "Connected devices", and do "Remove device". Then, plug your device again.
While this is less than ideal, it might help if you run Electrum as Administrator.
Debug message
No exceptions encountered.
As suggested, I tried running Electrum as administrator and the KeepKey connected without issue. I've been using Electrum 3.3.8 since it was released, and I haven't updated the firmware on my KeepKey since the last time I used it, but have a installed a few Windows 10 updates since then.
I doubt that KeepKey would do something to intentionally prevent Electrum compatibility. I'll submit a service request with KeepKey, perhaps It's as I suspect that one of the recent OS updates broke the connection between the KeepKey and Electrum.
ETA:
In the mean time you can use the sudo command in terminal to start Electrum. That's the equivalent to running it as administrator in Windows.
