In bloodbath times, I tend to think to take a loan and invest in few prominent currencies and leave it for few years. Then I realize what happened to Luna and realize there is nothing surefire here.
So, there is risk in taking loan but then reward is high, and there is sense of safety in not taking loan. You would be kind of free? Yes you didn't make much/took advantage of market downturn but you are free, you have nothing to worry for?
You can take a loan actually but don't use it to invest in crypto but rather put it into the investment where you can assure good profit at the end of the month (or at least).
However, if both parties will agree with the term and conditions being presented, then that's up to you then. But I suggest for you OP not to just focus on investing crypto this time. With that borrowed amount, I highly recommend splitting it in order to minimize risk, and at least, if ever you lose there is something that could be able to save you.