What are your thoughts about this and could this have a major effect?
I don't see any possible effect that this can have based on my calculations, as those cards are linked to users personal Binance accounts. Even if the use of the card has been limited, users can still have access to the funds on the account, and as such, they can use their login details to either withdraw the funds or fund their local bank account and complete whatever purchase they want to make.
The only place that there could have been a negative effect is if the card didn't have any physical accounts that users could fall back on when accessing their funds. Before Binance Card, there have been numerous crypto payment options, so this won't be a big deal to the crypto industry but might have a little negative profit effect on Binance as any fee that has been budgeted to be achieved from the card users will be cut.