What do you think, is owning a gambling site that profitable than becoming a mare gambler?
Is it profitable? It depends!
It depends on how much money you have to invest, because it all starts with creating a secure website that complies with regulations (assuming the site is 100% legal). Then there is the cost of acquiring a license, costs for advertising campaigns and bonuses to attract new players, because gaining reputation and trust nowadays is complicated, especially considering the high level of competition. And of course... you still need to maintain a sufficient cash balance to cover the checkout of a few lucky players who will quickly empty your account until you can generate revenue with new deposits.
If you have the money for all this and also know how to manage it well (you need experience in the field), then I would say it is possible to earn more money than with an easy bet, because the house advantage will be on your side, not against you.
But honestly, how many people do you think have this profile?