They are similar, but I think the biggest difference is expected value.
In gambling, the odds are usually designed so the house wins over time. Even if you get lucky short term, mathematically the player is disadvantaged in many games.
In meme coins, there is no fixed house edge, but there is often an information edge. Insiders, snipers, early wallets, influencers, and devs usually know more than retail buyers. That means late buyers are often the ones funding everyone else’s profit.
So both can be risky, but for different reasons:
Gambling = mathematical disadvantage
Meme coins = informational disadvantage
In both cases, people chasing fast money usually ignore risk management.
In layman's words, both are riskier investment and only those who want fast money go for those. Risk management never plays a bigger picture here as these people hardly care about the risks involved. They are blindfolded by the profits which they might or might not achieve in the near future. Risk always remains on top when it comes to investing in meme coins or even gambling for say.
Gambling never guarantees fixed profits are there are a number of ups and downs every gambler has to go through. In both the places, making profits would depend on the listed reasons or by luck.
I would still consider both the same even if they have different characteristics and way or operating. They are still the same for me where if I invest, will end up with nothing but regrets in hand so I would try to maintain my distance.