Most memecoins are not profitable, because they make fake profiles, the coin supply is high, and they try to create hype so that some people buy the coin. When they launch their coin and it is full of hype, then team members sell all their coins and get out of the platform. Sometimes they alert people that the coins are highly volatile, your money is at risk, and it is not refundable. Slowly the coin is going to be delisted. New people lose their money. So be alert about memecoins.
Memecoins always work like gambling with a rare chance of giving a return on investment because they have no use case, and devs work for their own interest; as they have something, they always dump them. Hype always works for them. Recently a few memecoins have given big losses to people just because of this; now they are avoiding them and do not have enough interest, but still many of those who always want to be rich quickly want to invest and take advantage of them.
There has never been any strategy for holding or buying; sometimes it works as people make early purchases and then wait for the right time to sell. It works, but not for days; it's always a matter of minutes or hours. This can give you a good return, but in case of failure, things can go against investors.