As I recall, when I first learned about Bitcoin, I could still see a GTX 1080 GPU as being profitable (though not very much).
Your memory is wrong or you were misled by someone else. According to Wikipedia, that GPU released in May 27, 2016. By that time, every miner only use ASIC.
Based on whattomine, it seems like the latest GPU series are mostly used for mining shitcoins nowadays.
Yeah. Other popular coin have moved from PoW (for example ETH moved to PoS), while Monero switched to RandomX which makes it's profitable only with CPU.
You might be thinking, "NiceHash" mining with GPU rewarded you in Bitcoin, but the fact is you are mining an altcoin they only pay you in Bitcoin. Before it is profitable around 2017, I build my gear at that time to mine ETH or mine in Nicehash. It was profitable until the price of coins dropped and mining with GPU was no longer profitable due to high electricity rates.
It's also worth to mention NiceHash have become worse platform since few years ago. I recall it's because some inactive/withdraw fee and identity verification even if you only mine and withdraw BTC.