I don't know about lakebtc, but I heard btc-e's fees are so high that buying bitcoin there is no cheaper than bitstamp. The trading and withdrawal fees usually account for the difference in price on the two exchanges.
aha, I also cannot understand why so many people trade in BTC-e which so high the deposit & withdraw fees like robbers, even we know nothing about it
according to https://bitcointalk.org/index.php?topic=695082.0Lakebtc seem to have a low fee and quite same volume as BTC-e
according to http://bitcoincharts.com/markets/