it might be better to really power the system off instead of rebooting - I noticed that when I "killed" a card by overclocking (seeking the highest stable speed) that a reboot did not suffice for the card to recover ...
That's a good idea. I noticed something similar that if a card if not detected for whatever reason, a reboot won't solve the issue. And shutting it down the then turning on again could make the card get detected.
I still haven't got a fix on the root cause of the issues I'm having, I'm still not sure it's the card that's getting locked or it's a motherboard that somehow remember the card/slot tha failed and won't let me boot up until I remove/replace that card.