I am fairly new to this and am just getting setup.
I am running 3 - antminer s1's right now hooked to Ethernet and have them mining with the interface that is internal to the antminer.
I am mining at Antpool, bitcoin.cz and multipool and use the interface at those sites for info and stats
Do I still need to run bitcoin mining software like cgminer, bfgminer or easy miner?
Is it more efficient to run the software on my local pc?
If so what software is best for these miners?
Depends on what miner you are using. Like KYLE said, antminer's are standalone, and you won't be required to run a mining software.