I've used them quite a bit in overloaded datacenters while proper chillers were down or in the process of being added.
You will have 3 major concerns:
1) Power - The Smallest units will run on 110 but, the majority will require 230.
2) Condensation - Small units will have a jug that will need to be emptied regularly. Mid-size units typically also have trays but can generally be used with a pump without too much hassle. The big units typically have integrated pumps.
3) Exhaust - You're going to need a place to run the exhaust duct to. Typically, the unit will come with a few feet of duct, just enough to run up to a standard height ceiling. You'll need to head to home depot if you need more than that.