It'll disrupt the marketplace in as much as the users will just flock to another one as what happened when alpha bay went down people just emigrated over to Dream and Hansa. When you take a marketplace down at least one more will pop up to replace it and they know this but continue with the charade any way. The only way they'll ever win this war is by legalising or decriminalise drugs or these sorts of marketplaces but can't see that ever happening.
It looks like the Dutch police got on Reddit and elsewhere and actively encouraged Alphabay lost souls to join Hansa so they could be nailed. Perhaps they've fatally holed trust in the concept until something P2P comes along.