I don't see a single 1500 watt power supply handling more than about 5 1080 ti at one time reliably (6 if they are FE cards *maybe* but that's pushing the supply to the limit).
 You MIGHT be able to push it to 6 (aftermarket) or 7 (FE) with a fairly hefty lowered TDP limit on all the cards but keep in mind that the cards run at 100% TDP and normal BIOS voltage when the rig first boots up, for a few secs at least, 'till whatever you're using to SET the lowered TDP kicks in - definitely put a sleep of at least 10 and preferably 20-30 seconds on the first line of your "start up the miner .bat file" to give everything else time to get going and initiated.

 1500 + 1200 should handle 8 comfortably - 1500 for 5 cards, 1200 for the other 3 cards + the rest of the system.


 Don't believe the "1080 Ti is a 250 watt TDP card" information - a LOT of the aftermarket cards set the TDP quite a bit higher to give them the OVERHEAD to be able to set those high "factory overclocks", and even on GAMING loads (which don't load up a GPU nearly as consistantly as mining does) a lot of review sites quote some of the 1080 ti cards as being MEASURED at 290 watts or so usage.

 Won't be any new RX 5xx models, but they BETTER get more cards shipping on the existing models!

 What the heck is a Bitsler?

 Is that some new small exchange?

 You have just run into one of the 2 biggest issues with Windows 10 - it's insistance on  (and the VERY HUGE pain of trying to get it to NOT) automatically updating things that BREAK software.

 Earlier versions of Windows had the SAME, FREQUENTLY AND OFTEN COMPLAINED ABOUT "feature" but earlier versions made it fairly easy to turn the autoupdate bug OFF - Windows 10 makes it a royal PITA, especially if you do NOT have PRO or "higher" varients.

 AMD also has an issue that ALL of their "relive" driver versions are junk bloatware to date, don't work well even on NEWER cards like the RX 470 and are absolute GARBAGE if you have R9/R7 or older series cards.

 These sort of issues are why I specifically recommend that dedicated mining machines should run LINUX - once you get a LINUX box up and running, it doesn't BREAK things for you and tends to STAY up a lot more of the time than Windows is capable of doing.



 To jddebug:

 For my Gigabyte Windforce R9 280x cards, I find that core clock 1100 and memory clock at 1250 seems to give optimal results (anything over 1250 mem clock seems to introduce too much latency, anything over 1100 core and they start crashing) - stock BIOS running 12.4 on XUbuntu LINIX gives me right at 300 sol/s per card (one a tick over, one a tick under) *IF* I can keep them cool enough - the heat wave we had last week had them into thermal limiting a few hours a day, due to the limited ventilation options on my current place.
 Your cards may vary, I've seen folks claiming to be able to clock R9 280x as high as 1200, but I don't know if they had "factory stock" cooling on them to achieve that, or perhaps just better luck in the ASIC quality lottery (mine are both mid-grade).

 I doubt anyone you're seeing in the 290 sol/s range are running stock clocks AND stock BIOS.

 My cards are not undervolted - and in the testing I've done on them they seem to be locked on voltage in the BIOS, as they just shrugged off my efforts to undervolt them when I had them in a Windows machine with Afterburner, so seems like BIOS mod or flash with a UV-specific BIOS are the only options (this makes sense, as my R9 290 cards were DEFINITELY voltage-locked in the BIOS and I had to flash them with a BIOS from TheStilt to get them to undervolt).

 I might be impressed if I had ever heard of "Bitsler".

 I presume that's an exchange?

 WhatToMine has individual coin calculators that include some or all of the skein coins - DGB-skein is one of them.
 I'm not sure why they don't include Skein as one of the algos on their "gpu comparative" page.

 If you are trying to use it on SHA256 you have so little hashrate you are not able to generate any shares.

 180 Mhash/sec by current standards in SHA256 isn't even noticeable - a SINGLE Antminer S5 (2 generations old ASIC and OUTDATED to the point of being unprofitable except on FREE electricity since the block reward halfing last summer) generated over 1000 MHash, current S9 units generate over 12000.

 Also, you appear to be trying to mine on a laptop - laptops do NOT handle the heat generated by heavy-duty usage (like cryptocoin mining does) on the GPU very well at all for long and will commonly overheat and sometimes die as a result.

While classing CureCoin (and FoldingCoin and to a much lesser degree GridCoin) as "legal bribes" is technically correct, the term "bribe" has enough negative associations that it's REALLY A BAD IDEA to talk about them that way.


 Curecoin *IS* useful for buying folding gear - just not DIRECTLY, you have to swap it into BitCoin first.
 Directly WOULD be an improvement - but higher value for CureCoin would help even more.


 Given EVGA's long committment to *some* support for Folding@Home, I don't think it's ENTIRELY implausable that they could be convinced to support CureCoin instead of their current "Folding Bucks" program, as long as you don't mind them BRAGGING about such support (which would end up being some mighty cheap advertising *IF* they could be convinced to support CureCoin) - this seems like an increasingly likely option as they slowly lose ground to, and eventually get passed, by Team Curecoin.

 Their current program already requires folks to join a specific team - and then jump through a significant number of other hoops - to get their rewards - and RIGHT NOW their rewards are quite a bit less than folding for CureCoin pays out for the same amount of points earned (much less CURE + FLDC).

 If they could be convinced to buy a fixed amount of CureCoin equal to their average expenditure per month in recent months for the EVGA Bucks program, in exchange for being allowed to ADVERTISE and BRAG about how they are supporting Folding@Home through their support for CureCoin, it could be a win-win situation for both groups - EVGA gets to budget a fixed amount a month instead of having no idea how much they're going to have to give credits for, and CureCoin gets a regular infusion of coin bought to support the price.
 
 The question then becomes "what happens to the CureCoin that EVGA bought", which is the big sticking point I can see to the whole idea.


 BTW, it appears that the Gates foundation isn't exactly opposed to supporting @Home related work.

 https://www.genomeweb.com/informatics/gates-foundations-hiv-grant-catapults-rosetta-protein-folding-software-vaccine-d-0

 from over a decade ago.

My R9 280x and R9 290 are pretty close to your 380 (it's a rebrand with slightly faster memory, the SAME GPU, and a bios upgrade of the R9 280 as I recall).
Both models have run Claymore 12.4 for (ZEC), genoil or qtminer (ETH) for me without issues on the 15.12 drivers.

 IMO don't even look at any "relive" driver for anything older than the RX 5xx series, and don't bother with the 16.x series of drivers on anything older than the RX 4xx series or the Fury line.

 There were quite a few of the 16.x driver series that FLAT OUT WOULD NOT WORK if you have a modded bios - 16.9.x and 16.10.x do work with modded bios, but I only recommend 16.10.1 WHQL usage for those folks with newer cards than yours.



 

2 PSU would be a viable option - a pair of the EVGA G2 1000 has a total of 12 x 6+2 and 4 x 6 pin, would have to use a couple of 2xmolex-to-PCI-E 6-pin adapters for 2 of the risers I think, or dig up 2 spare "y" cables (the supply itself has 6 connectors for VGA power, but apparently has 4 single PCI-E 6+2 and 2 "Y" 6+2 and 6 cables).

 EVGA G2 series all use the same cables, you CAN mix-and-match among them.

I've got machines with the A10-7860 and A10-7890K running on the 15.12 drivers - one of which has a HD 7850 in it (semi-short card to leave airflow to the middle card in the system, a GTX 1070).

 Anything before the A12 series should work, the A12 probably needs something newer as those were released AFTER the 15.12 drivers were released.

ETH likes MEMORY speed, CPU speed doesn't matter that much in most cases as long as you don't go WAY WAY underclocked.

 I wish I could push the memory on my Sapphires higher, but the one time I tried them at 1800 was crash crash crash city.

 Only reason the core is pushed at all is that a lot of the algos they mine via NiceHash DO like higher core clocks.

Burst should be mineable on a Pi - but I wouldn't try to mine a BIG drive with a Pi, they're quite slow.

 The expansion is reported to use the Archive internally.

 http://www.storagereview.com/seagate_backup_plus_external_hard_drive_review_8tb

 among other sources.

 Wierd that it's selling for quite a bit less than the bare drive.

Use the 480 - your GTX 460 is lower performance by a lot vs my HD 7750, which was barely faster than 3 cores on my A10-5700.

 Your FX should be close to the CPU side of my A10-5700 - which was managing somewhat in excess of 1 but less than 2 TB a day with an AVX plotter on 3 cores.

 RX 480 should be limited by the speed of the drives themselves.

 EVGA sells "cable kits" for their power supplies - fairly cheap and same or better quality as the cables they ship with the PS, and not REAL expensive.

  TDP of the Aorus appears to be around 280 watts, per what I can find in reviews of it on the net, which would be about 225 out of the PCI-E connectors. Using a "Y" cable with 2 8-pin connectors on it should be OK, EVGA cables tend to have very few issues even loaded down with ASIC machines pushing the cables to 300+ watts per cable (and those are usually due to someone trying to push 300+ watts through a 6-pin connector, which is out of spec for the connector itself much less PCI-E specs or the cable limits).

 250 watts would be a 1080 Ti Founders Edition or some of the aftermarket not-highly-overclocked varients - a LOT of the Gigabyte GTX 10xx series cards are "factory overclocked" quite high with a 10% or so higher TDP limit, and the AORUS series seems to ALL be that way.

 I would NOT make the "go ahead and use the Y cables" recommendation with *some* brands of power supply, however, or some REALLY HIGH TDP GPU cards.


 One thing to watch closely though - 6 x Aorus at 100% ARE probably an overload for the power supply as a whole if you're pushing them hard, like most cryptocoins do. You MIGHT want to think seriously about runnning 5 of them, or going with 1 or 2 lower-level cards. Some of the reviews I saw were showing 290ish watt usage on GAMING loads at peak - mining some cryptocoins put MORE load and use MORE power on AVERAGE than most peak gaming loads can manage.

 Make sure you check actual power consumption at the 4 and 5 card levels before you add the 6'th card.


 There are places that sell adapters to go from a pair of 6-pin PCI-E to a single 8-pin - but those shouldn't be needed in your case.

If it doesn't jump that much, it will be due to the massive price "correction" the last day or so.

The last 2 diff jumps have both been pretty close to 7% (one over one under), the one we're working on now looks to be close to that when it finishes (it's a bit OVER right now per bitcoinwisdom, was 7.6 when I asked for the 7.0% spot) - I don't see any reason other than Bitmain AND at least 2 of the other miner makers run out of chips for at least the next week for it to be a lot lower.

 8-O


 On the other hand, the current "correction" on Bitcoin price might convince a few would-be miner buyers to hold off.
 Or it might get them wanting to buy faster to stock up more coin before the next surge hits.....

If you keep the TDP *reliably* turned down to under 145 or so watts per card, a 6 card 1070 rig should be OK on a good 1000 watt PS like the EVGA G2 or a Seasonic X-series.

 I would NOT build the rig that way though, too many algos need more power per card especially on the higher-end 1070 models that have a 180 watt TDP.

 5 x 1070 on a single good-quality 1000 watt PS should be generally safe.



 All EVGA G2 and Seasonic X-series PS are dual-conversion - specifically including the 650 and 750 watt models.

 THE easy way to tell a dual-conversion supply is look at the max 12VDC load specification - if it is the same or within a couple watts of the max for the entire supply it's dual-conversion.


 G2 and X series are quite comfortable at 90+% of rated load 24/7 - this is true for MOST power supplies at and above the 1KW level and for supplies in a "series" that has a 1KW or higher model at the high end of the "series".


 Interesting point - the last 2 models of the Backblaze "pod" use the EVGA G2 750 - I don't know what their "v7.0" model is going to move to if/when they decide to come up with it, or what they are going to move their v6.0 pod construction to when they can no longer GET the discontinued G2 model PS.

+7.0%

The only current USB device with a significant chance of profitability would be the Moonlander for Scrypt (and even there, ROI is going to take forever unless you can get it VERY cheap).

 That should change fairly shortly when Sidehack gets his BitFury-based pod miner project working and up for sale.