I've asked your question to my friend and he said
I've been using Minergate for about five months now. We have three MacBook Pros in the house so I connected them all to one account via log in and I mine! Granted I can only mine via CPU and I'm probably mining at a loss most of the time, occasionally I luck out with the pools.
The hash rate can vary by coin, and I spend most of my time dual mining Fantomcoin and DSH or FCN and Quazarcoin. However this month Monero and ETC are mining at a substantial profit.
Minergate being the only simple GUI set up for Mac I enjoy myself regardless.
If you have a desktop and can mine continuously via both CPU & GPU I feel pretty strongly that the profits would be substantial.
Either way it's a great way to get started.