I work with Hi-def video so it would be nice if I could build a video editing workstation that could also mine efficiently, but I guess that's not in the cards yet.
Similarly, I run a top 500 folding team and as of yet the ATI client is not nearly as good as the NVidia one so at first I was just diverting GPU from my folding efforts to mining. In the end I picked up a 6990 and popped it in my main folding box. It mines about twice as well than the three GTX4/580's I was diverting. It's almost paid for too, but that was because I cashed out some BTC @ $29/ ;-)