Will connecting 4 or 5 ATI 280x card fit in some mobo?
Have you seen something like this?
You could be the amount of heat out of 4 cards that will be side by side is going to kill your equipment even if you use a small shunt to try and space them alittle, go with risers and an open frame. Even if you think you might save alittle money you really wont once you have to deal with RMAs for cards with dead VRMs/GPUs/Motherboards from all the heat.
(I have 4 cards in a milk crate with risers and still have trouble moving all the heat)